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[[Image:3spa.png|left|200px]]


{{STRUCTURE_3spa|  PDB=3spa  |  SCENE=  }}
==Crystal Structure of Human Mitochondrial RNA Polymerase==
 
<StructureSection load='3spa' size='340' side='right'caption='[[3spa]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
===Crystal Structure of Human Mitochondrial RNA Polymerase===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3spa]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SPA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SPA FirstGlance]. <br>
{{ABSTRACT_PUBMED_21947009}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3spa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3spa OCA], [https://pdbe.org/3spa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3spa RCSB], [https://www.ebi.ac.uk/pdbsum/3spa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3spa ProSAT]</span></td></tr>
[[3spa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SPA OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/RPOM_HUMAN RPOM_HUMAN] DNA-dependent RNA polymerase catalyzes the transcription of mitochondrial DNA into RNA using the four ribonucleoside triphosphates as substrates.<ref>PMID:21278163</ref>


==See Also==
==See Also==
*[[Molecular Playground/Human mtRNA pol|Molecular Playground/Human mtRNA pol]]
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
*[[RNA polymerase|RNA polymerase]]
== References ==
 
<references/>
==Reference==
__TOC__
<ref group="xtra">PMID:021947009</ref><references group="xtra"/>
</StructureSection>
[[Category: DNA-directed RNA polymerase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Cramer, P.]]
[[Category: Large Structures]]
[[Category: Litonin, D.]]
[[Category: Cramer P]]
[[Category: Morozov, Y I.]]
[[Category: Litonin D]]
[[Category: Ringel, R.]]
[[Category: Morozov YI]]
[[Category: Sologub, M.]]
[[Category: Ringel R]]
[[Category: Temiakov, D.]]
[[Category: Sologub M]]
[[Category: Mitochondria]]
[[Category: Temiakov D]]
[[Category: Single-subunit dna-dependent rna polymerase in mitochondria]]
[[Category: Transferase]]

Latest revision as of 13:03, 14 March 2024

Crystal Structure of Human Mitochondrial RNA Polymerase

3spa, resolution 2.50Å

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