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[[Image:3ge1.png|left|200px]]


{{STRUCTURE_3ge1|  PDB=3ge1  |  SCENE=  }}
==2.7 Angstrom Crystal Structure of Glycerol Kinase (glpK) from Staphylococcus aureus in Complex with ADP and Glycerol==
 
<StructureSection load='3ge1' size='340' side='right'caption='[[3ge1]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
===2.7 Angstrom Crystal Structure of Glycerol Kinase (glpK) from Staphylococcus aureus in Complex with ADP and Glycerol===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3ge1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_COL Staphylococcus aureus subsp. aureus COL]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GE1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GE1 FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
[[3ge1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_col Staphylococcus aureus subsp. aureus col]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GE1 OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ge1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ge1 OCA], [https://pdbe.org/3ge1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ge1 RCSB], [https://www.ebi.ac.uk/pdbsum/3ge1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ge1 ProSAT], [https://www.topsan.org/Proteins/CSGID/3ge1 TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GLPK_STAAC GLPK_STAAC] Key enzsyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate (By similarity).[HAMAP-Rule:MF_00186]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ge/3ge1_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ge1 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Glycerol kinase|Glycerol kinase]]
*[[Glycerol kinase|Glycerol kinase]]
[[Category: Glycerol kinase]]
__TOC__
[[Category: Staphylococcus aureus subsp. aureus col]]
</StructureSection>
[[Category: Anderson, W F.]]
[[Category: Large Structures]]
[[Category: Brunzelle, J.]]
[[Category: Staphylococcus aureus subsp. aureus COL]]
[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
[[Category: Anderson WF]]
[[Category: Minasov, G.]]
[[Category: Brunzelle J]]
[[Category: Onopriyenko, O.]]
[[Category: Minasov G]]
[[Category: Peterson, S N.]]
[[Category: Onopriyenko O]]
[[Category: Savchenko, A.]]
[[Category: Peterson SN]]
[[Category: Skarina, T.]]
[[Category: Savchenko A]]
[[Category: Adp]]
[[Category: Skarina T]]
[[Category: Atp-binding]]
[[Category: Center for structural genomics of infectious disease]]
[[Category: Csgid]]
[[Category: Glycerol]]
[[Category: Glycerol kinase]]
[[Category: Glycerol metabolism]]
[[Category: Idp00743]]
[[Category: Kinase]]
[[Category: Nucleotide-binding]]
[[Category: Structural genomic]]
[[Category: Transferase]]

Latest revision as of 07:04, 6 September 2023

2.7 Angstrom Crystal Structure of Glycerol Kinase (glpK) from Staphylococcus aureus in Complex with ADP and Glycerol

3ge1, resolution 2.70Å

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