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[[Image:3lch.png|left|200px]]


{{STRUCTURE_3lch|  PDB=3lch  |  SCENE=  }}
==The D-sialic acid aldolase mutant V251R==
 
<StructureSection load='3lch' size='340' side='right'caption='[[3lch]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
===The D-sialic acid aldolase mutant V251R===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3lch]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LCH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LCH FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.04&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
[[3lch]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LCH OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lch FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lch OCA], [https://pdbe.org/3lch PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lch RCSB], [https://www.ebi.ac.uk/pdbsum/3lch PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lch ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NANA_ECOLI NANA_ECOLI] Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate.[HAMAP-Rule:MF_01237]


==See Also==
==See Also==
*[[Aldolase|Aldolase]]
*[[N-acetylneuraminate lyase 3D structures|N-acetylneuraminate lyase 3D structures]]
[[Category: Escherichia coli]]
__TOC__
[[Category: N-acetylneuraminate lyase]]
</StructureSection>
[[Category: Chou, C Y.]]
[[Category: Escherichia coli K-12]]
[[Category: Ko, T P.]]
[[Category: Large Structures]]
[[Category: Wang, A H.J.]]
[[Category: Chou C-Y]]
[[Category: Carbohydrate metabolism]]
[[Category: Ko T-P]]
[[Category: Lyase]]
[[Category: Wang AH-J]]
[[Category: Schiff base]]
[[Category: Tim barrel]]

Latest revision as of 16:22, 1 November 2023

The D-sialic acid aldolase mutant V251R

3lch, resolution 2.04Å

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