1etw: Difference between revisions
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==THE CRYSTAL STRUCTURE OF E. COLI FIS MUTANT G72D== | |||
<StructureSection load='1etw' size='340' side='right'caption='[[1etw]], [[Resolution|resolution]] 2.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1etw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ETW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ETW FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1etw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1etw OCA], [https://pdbe.org/1etw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1etw RCSB], [https://www.ebi.ac.uk/pdbsum/1etw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1etw ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/FIS_ECOLI FIS_ECOLI] Activates ribosomal RNA transcription, as well other genes. Plays a direct role in upstream activation of rRNA promoters. Binds to a recombinational enhancer sequence that is required to stimulate hin-mediated DNA inversion. Prevents initiation of DNA replication from oriC.<ref>PMID:2209559</ref> <ref>PMID:8836178</ref> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/et/1etw_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1etw ConSurf]. | |||
<div style="clear:both"></div> | |||
== | ==See Also== | ||
*[[FIS protein|FIS protein]] | |||
== References == | |||
<references/> | |||
[[ | __TOC__ | ||
</StructureSection> | |||
== | |||
< | |||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Cheng YS]] | ||
[[Category: | [[Category: Johnson RC]] | ||
[[Category: | [[Category: Yang WZ]] | ||
[[Category: | [[Category: Yuan HS]] | ||
Latest revision as of 07:06, 7 February 2024
THE CRYSTAL STRUCTURE OF E. COLI FIS MUTANT G72D
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