1x41: Difference between revisions

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[[Image:1x41.png|left|200px]]


{{STRUCTURE_1x41|  PDB=1x41  |  SCENE=  }}
==Solution structure of the Myb-like DNA binding domain of human Transcriptional adaptor 2-like, isoform B==
 
<StructureSection load='1x41' size='340' side='right'caption='[[1x41]]' scene=''>
===Solution structure of the Myb-like DNA binding domain of human Transcriptional adaptor 2-like, isoform B===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1x41]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X41 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X41 FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x41 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x41 OCA], [https://pdbe.org/1x41 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x41 RCSB], [https://www.ebi.ac.uk/pdbsum/1x41 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x41 ProSAT], [https://www.topsan.org/Proteins/RSGI/1x41 TOPSAN]</span></td></tr>
[[1x41]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X41 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/TAD2A_HUMAN TAD2A_HUMAN] Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling.<ref>PMID:19103755</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x4/1x41_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1x41 ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Inoue, M.]]
[[Category: Large Structures]]
[[Category: Kigawa, T.]]
[[Category: Inoue M]]
[[Category: Koshiba, S.]]
[[Category: Kigawa T]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Koshiba S]]
[[Category: Sasagawa, A.]]
[[Category: Sasagawa A]]
[[Category: Sato, M.]]
[[Category: Sato M]]
[[Category: Yokoyama, S.]]
[[Category: Yokoyama S]]
[[Category: Myb domain]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Riken structural genomics/proteomics initiative]]
[[Category: Rsgi]]
[[Category: Structural genomic]]
[[Category: Transcription]]
[[Category: Transcriptional activation]]
[[Category: Transcriptional adaptor protein2]]
Retrieved from "https://proteopedia.org/1x41"