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[[Image:2ffz.png|left|200px]]


{{STRUCTURE_2ffz| PDB=2ffz | SCENE= }}
==Structural Studies Examining the Substrate Specificity Profiles of PC-PLCBc Protein Variants==
<StructureSection load='2ffz' size='340' side='right'caption='[[2ffz]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2ffz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_cereus Bacillus cereus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FFZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FFZ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ffz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ffz OCA], [https://pdbe.org/2ffz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ffz RCSB], [https://www.ebi.ac.uk/pdbsum/2ffz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ffz ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PHLC_BACCE PHLC_BACCE] Required, with sphingomyelinase, to effect target cell lysis (hemolysis).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ff/2ffz_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ffz ConSurf].
<div style="clear:both"></div>


===Structural Studies Examining the Substrate Specificity Profiles of PC-PLCBc Protein Variants===
==See Also==
 
*[[Phospholipase C|Phospholipase C]]
{{ABSTRACT_PUBMED_17324372}}
__TOC__
 
</StructureSection>
==About this Structure==
[[2ffz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_cereus Bacillus cereus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FFZ OCA].
 
==Reference==
<ref group="xtra">PMID:017324372</ref><references group="xtra"/>
[[Category: Bacillus cereus]]
[[Category: Bacillus cereus]]
[[Category: Phospholipase C]]
[[Category: Large Structures]]
[[Category: Antikainen, N M.]]
[[Category: Antikainen NM]]
[[Category: Benfield, A B.]]
[[Category: Benfield AB]]
[[Category: Martin, S F.]]
[[Category: Martin SF]]
[[Category: Hydrolase]]
[[Category: Pc-plcbc protein variant]]
[[Category: Substrate specificity]]

Latest revision as of 09:23, 14 February 2024

Structural Studies Examining the Substrate Specificity Profiles of PC-PLCBc Protein Variants

2ffz, resolution 2.05Å

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