2f5u: Difference between revisions

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[[Image:2f5u.png|left|200px]]


{{STRUCTURE_2f5u|  PDB=2f5u  |  SCENE=  }}
==Structural Characterization of the UL25 DNA Packaging Protein from Herpes Simplex Virus Type 1==
 
<StructureSection load='2f5u' size='340' side='right'caption='[[2f5u]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
===Structural Characterization of the UL25 DNA Packaging Protein from Herpes Simplex Virus Type 1===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2f5u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_alphaherpesvirus_1 Human alphaherpesvirus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F5U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F5U FirstGlance]. <br>
{{ABSTRACT_PUBMED_16474137}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f5u OCA], [https://pdbe.org/2f5u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f5u RCSB], [https://www.ebi.ac.uk/pdbsum/2f5u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f5u ProSAT]</span></td></tr>
==About this Structure==
</table>
[[2f5u]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_herpesvirus_1 Human herpesvirus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F5U OCA].  
== Function ==
 
[https://www.uniprot.org/uniprot/CVC2_HHV11 CVC2_HHV11] Capsid vertex-specific component that plays a role during viral DNA encapsidation, assuring correct genome cleavage and presumably stabilizing capsids that contain full-length viral genomes. Participates in the interaction between the capsid and the tegument through interaction with the large tegument protein/LTP. May mediate the capsid docking to the nuclear pore allowing entry of the viral genome into the host nucleus through binding to host nucleoporins NUP214.[HAMAP-Rule:MF_04025]<ref>PMID:18448531</ref> <ref>PMID:18945788</ref>
==Reference==
== Evolutionary Conservation ==
<ref group="xtra">PMID:016474137</ref><references group="xtra"/>
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Human herpesvirus 1]]
Check<jmol>
[[Category: Bowman, B R.]]
  <jmolCheckbox>
[[Category: Capsid protein]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f5/2f5u_consurf.spt"</scriptWhenChecked>
[[Category: Dna packaging]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Head completion]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Hsv-1]]
  </jmolCheckbox>
[[Category: Ul25]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f5u ConSurf].
[[Category: Viral protein]]
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Human alphaherpesvirus 1]]
[[Category: Large Structures]]
[[Category: Bowman BR]]
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