3ga7: Difference between revisions

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[[Image:3ga7.png|left|200px]]


{{STRUCTURE_3ga7|  PDB=3ga7  |  SCENE=  }}
==1.55 Angstrom Crystal Structure of an Acetyl Esterase from Salmonella typhimurium==
 
<StructureSection load='3ga7' size='340' side='right'caption='[[3ga7]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
===1.55 Angstrom Crystal Structure of an Acetyl Esterase from Salmonella typhimurium===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3ga7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GA7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GA7 FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
[[3ga7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GA7 OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ga7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ga7 OCA], [https://pdbe.org/3ga7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ga7 RCSB], [https://www.ebi.ac.uk/pdbsum/3ga7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ga7 ProSAT], [https://www.topsan.org/Proteins/CSGID/3ga7 TOPSAN]</span></td></tr>
[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
</table>
[[Category: Anderson, W F.]]
== Function ==
[[Category: Brunzelle, J.]]
[https://www.uniprot.org/uniprot/AES_SALTY AES_SALTY] Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons). Able to hydrolyze triacetylglycerol (triacetin) and tributyrylglycerol (tributyrin), but not trioleylglycerol (triolein) or cholesterol oleate. Negatively regulates MalT activity by antagonizing maltotriose binding. Inhibits MelA galactosidase activity (By similarity).
[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
== Evolutionary Conservation ==
[[Category: Minasov, G.]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Onopriyenko, O.]]
Check<jmol>
[[Category: Peterson, S N.]]
  <jmolCheckbox>
[[Category: Savchenko, A.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ga/3ga7_consurf.spt"</scriptWhenChecked>
[[Category: Skarina, T.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: Wawrzak, Z.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Acetyl esterase]]
  </jmolCheckbox>
[[Category: Center for structural genomics of infectious disease]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ga7 ConSurf].
[[Category: Csgid]]
<div style="clear:both"></div>
[[Category: Hydrolase]]
__TOC__
[[Category: Idp00896]]
</StructureSection>
[[Category: Phosphoserine]]
[[Category: Large Structures]]
[[Category: Serine esterase]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
[[Category: Structural genomic]]
[[Category: Anderson WF]]
[[Category: Brunzelle J]]
[[Category: Minasov G]]
[[Category: Onopriyenko O]]
[[Category: Peterson SN]]
[[Category: Savchenko A]]
[[Category: Skarina T]]
[[Category: Wawrzak Z]]
Retrieved from "https://proteopedia.org/3ga7"