Erythrocyte binding antigen: Difference between revisions

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[[Image:1zro.png|left|200px|thumb|Crystal Structure of EBA region II (mutant) complex with sialic acid derivative, [[1zro]]]]
<StructureSection load='1zro' size='350' side='right' scene='' caption='EBA region II (mutant) complex with sulfate and Cl- ion (PDB code [[1zro]]) '>
{{STRUCTURE_1zro|  PDB=1zro | SIZE=400| SCENE= |right|CAPTION=EBA region II (mutant) complex with sialic acid derivative, [[1zro]] }}
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 




'''Erythrocyte binding antigen''' or '''Duffy receptor''' (EBA) is a ''Plasmodium'' ligand which binds to erythrocytes.  Some strains are dependent on sialic acid for binding<ref>PMID:22989878</ref>. 
*'''EBA-175''' is a ''Plamodium'' ligand that binds to human erythrocytes glycophorin A in a sialic acid-dependent manner<ref>PMID:12672957</ref>.
*'''EBA-140''' is a ''Plamodium'' ligand that binds to human erythrocytes glycophorin C <ref>PMID:22989878</ref>.  For more details see [[Malaria Parasite Plasmodium falciparum Erythrocyte Binding Antigen 140]].
*'''Duffy receptor''' is a glycogen receptor for chemicals secreted by blood cells and for ''Plamodium'' ligand <ref>PMID:25108177</ref>.
</StructureSection>


== 3D Structures of erythrocyte binding antigen ==


Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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'''Erythrocyte binding antigen''' (EBA) is a ‘’Plasmodium falciparum’’ ligand which binds to erythrocytes.  Some strains are dependent on sialic acid for binding.  For more details see [[Malaria Parasite Plasmodium falciparum Erythrocyte Binding Antigen 140]].
*EBA-175


== 3D Structures of erythrocyte binding antigen ==
**[[1zrl]], [[1zro]] – PfEBA region II (mutant) - ''Plasmodium falciparum''<br />
**[[2rji]] – PfEBA region VI <br />
**[[4k2u]] – PfEBA + antibody<br />
**[[4qex]] – PfEBA (mutant) + antibody<br />


Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
*EBA-140


===EBA-175===
**[[4gf2]], [[4jno]] – PfEBA (mutant) <br />


[[1zrl]] – EBA region II (mutant) <br />
*Duffy receptor region II 198-525
[[1zro]] – EBA region II (mutant) + sialic acid derivative<br />
[[2rji] – EBA region VI <br />


===EBA-140===
**[[5x6n]] – EBA region II – ''Plasmodium knowlesi'' <br />
**[[3rrc]], [[4yfs]] – PvEBA region II – ''Plasmodium vivax'' <br />
**[[5f3j]], [[6oan]], [[6oao]], [[6r2s]] – PvEBA region II + antibody<br />
**[[4nuu]], [[4nuv]] – PvEBA region II + Duffy antigen/chemokine receptor<br />
}}
== References ==
<references/>


[[4gf2]] – EBA (mutant) <br />
[[Category:Topic Page]]
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