2wns: Difference between revisions

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{{STRUCTURE_2wns|  PDB=2wns  |  SCENE=  }}
==HUMAN OROTATE PHOSPHORIBOSYLTRANSFERASE (OPRTASE) DOMAIN OF URIDINE 5'-MONOPHOSPHATE SYNTHASE (UMPS) IN COMPLEX WITH ITS SUBSTRATE OROTIDINE 5'-MONOPHOSPHATE (OMP)==
===HUMAN OROTATE PHOSPHORIBOSYLTRANSFERASE (OPRTASE) DOMAIN OF URIDINE 5'-MONOPHOSPHATE SYNTHASE (UMPS) IN COMPLEX WITH ITS SUBSTRATE OROTIDINE 5'-MONOPHOSPHATE (OMP)===
<StructureSection load='2wns' size='340' side='right' caption='[[2wns]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[2wns]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WNS FirstGlance]. <br>
[[2wns]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNS OCA].  
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=OMP:OROTIDINE-5-MONOPHOSPHATE'>OMP</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2jgy|2jgy]], [[2v30|2v30]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotate_phosphoribosyltransferase Orotate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.10 2.4.2.10] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wns FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wns OCA], [http://pdbe.org/2wns PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wns RCSB], [http://www.ebi.ac.uk/pdbsum/2wns PDBsum]</span></td></tr>
</table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wn/2wns_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wns ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Phosphoribosyltransferase|Phosphoribosyltransferase]]
*[[Phosphoribosyltransferase|Phosphoribosyltransferase]]
*[[Uridine 5'-monophosphate synthase|Uridine 5'-monophosphate synthase]]
*[[Uridine 5'-monophosphate synthase|Uridine 5'-monophosphate synthase]]
[[Category: Homo sapiens]]
__TOC__
</StructureSection>
[[Category: Human]]
[[Category: Orotate phosphoribosyltransferase]]
[[Category: Orotate phosphoribosyltransferase]]
[[Category: Arrowsmith, C H.]]
[[Category: Arrowsmith, C H]]
[[Category: Berglund, H.]]
[[Category: Berglund, H]]
[[Category: Bountra, C.]]
[[Category: Bountra, C]]
[[Category: Collins, R.]]
[[Category: Collins, R]]
[[Category: Edwards, A M.]]
[[Category: Edwards, A M]]
[[Category: Flodin, S.]]
[[Category: Flodin, S]]
[[Category: Flores, A.]]
[[Category: Flores, A]]
[[Category: Graslund, S.]]
[[Category: Graslund, S]]
[[Category: Hammarstrom, M.]]
[[Category: Hammarstrom, M]]
[[Category: Johansson, A.]]
[[Category: Johansson, A]]
[[Category: Johansson, I.]]
[[Category: Johansson, I]]
[[Category: Karlberg, T.]]
[[Category: Karlberg, T]]
[[Category: Kotyenova, T.]]
[[Category: Kotyenova, T]]
[[Category: Kotzch, A.]]
[[Category: Kotzch, A]]
[[Category: Moche, M.]]
[[Category: Moche, M]]
[[Category: Nielsen, T K.]]
[[Category: Nielsen, T K]]
[[Category: Nordlund, P.]]
[[Category: Nordlund, P]]
[[Category: Nyman, T.]]
[[Category: Nyman, T]]
[[Category: Persson, C.]]
[[Category: Persson, C]]
[[Category: Roos, A.]]
[[Category: Roos, A]]
[[Category: Sagemark, J.]]
[[Category: Sagemark, J]]
[[Category: Schueler, H.]]
[[Category: Schueler, H]]
[[Category: Schutz, P.]]
[[Category: Schutz, P]]
[[Category: Siponen, M I.]]
[[Category: Siponen, M I]]
[[Category: Svensson, L.]]
[[Category: Svensson, L]]
[[Category: Thorsell, A G.]]
[[Category: Thorsell, A G]]
[[Category: Tresaugues, L.]]
[[Category: Tresaugues, L]]
[[Category: Vandenberg, S.]]
[[Category: Vandenberg, S]]
[[Category: Weigelt, J.]]
[[Category: Weigelt, J]]
[[Category: Welin, M.]]
[[Category: Welin, M]]
[[Category: Wisniewska, M.]]
[[Category: Wisniewska, M]]
[[Category: Decarboxylase]]
[[Category: Decarboxylase]]
[[Category: Disease mutation]]
[[Category: Disease mutation]]

Latest revision as of 23:13, 9 February 2016

HUMAN OROTATE PHOSPHORIBOSYLTRANSFERASE (OPRTASE) DOMAIN OF URIDINE 5'-MONOPHOSPHATE SYNTHASE (UMPS) IN COMPLEX WITH ITS SUBSTRATE OROTIDINE 5'-MONOPHOSPHATE (OMP)

2wns, resolution 1.90Å

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