4ksb: Difference between revisions
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==Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain== | |||
<StructureSection load='4ksb' size='340' side='right'caption='[[4ksb]], [[Resolution|resolution]] 3.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4ksb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KSB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KSB FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.8001Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ksb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ksb OCA], [https://pdbe.org/4ksb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ksb RCSB], [https://www.ebi.ac.uk/pdbsum/4ksb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ksb ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/MDR1A_MOUSE MDR1A_MOUSE] Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.<ref>PMID:19325113</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | |||
[[Category: Caya A]] | |||
[[Category: Chang G]] | |||
[[Category: Cregger C]] | |||
[[Category: Doshi R]] | |||
[[Category: Falson P]] | |||
[[Category: Govaerts C]] | |||
[[Category: Grimard V]] | |||
[[Category: Lee C-W]] | |||
[[Category: Martinez L]] | |||
[[Category: Pardon E]] | |||
[[Category: Steyaert J]] | |||
[[Category: Swartz DJ]] | |||
[[Category: Szewczyk P]] | |||
[[Category: Urbatsch I]] | |||
[[Category: Villaluz M]] | |||
[[Category: Ward A]] | |||
Latest revision as of 12:15, 1 March 2024
Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain
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