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{{STRUCTURE_4ee1|  PDB=4ee1  |  SCENE=  }}
===The structure of the S. aureus DnaG RNA Polymerase Domain bound to CTP and Manganese===
{{ABSTRACT_PUBMED_22795082}}


==Function==
==The structure of the S. aureus DnaG RNA Polymerase Domain bound to CTP and Manganese==
[[http://www.uniprot.org/uniprot/PRIM_STAAU PRIM_STAAU]] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis.  
<StructureSection load='4ee1' size='340' side='right'caption='[[4ee1]], [[Resolution|resolution]] 2.02&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[4ee1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EE1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EE1 FirstGlance]. <br>
[[4ee1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EE1 OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.02&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEN:BENZAMIDINE'>BEN</scene>, <scene name='pdbligand=CTP:CYTIDINE-5-TRIPHOSPHATE'>CTP</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ee1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ee1 OCA], [https://pdbe.org/4ee1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ee1 RCSB], [https://www.ebi.ac.uk/pdbsum/4ee1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ee1 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DNAG_STAAU DNAG_STAAU] RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.[HAMAP-Rule:MF_00974]


==See Also==
==See Also==
*[[RNA polymerase|RNA polymerase]]
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:022795082</ref><references group="xtra"/><references/>
[[Category: Large Structures]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
[[Category: Berger, J M.]]
[[Category: Berger JM]]
[[Category: Chu, C.]]
[[Category: Chu C]]
[[Category: Corn, J E.]]
[[Category: Corn JE]]
[[Category: Rymer, R U.]]
[[Category: Rymer RU]]
[[Category: Solorio, F A.]]
[[Category: Solorio FA]]
[[Category: Wang, J D.]]
[[Category: Wang JD]]
[[Category: Bacterial]]
[[Category: Catalytic domain]]
[[Category: Nucleoside polyphosphate]]
[[Category: Nucleoside triphosphate]]
[[Category: Nucleotide]]
[[Category: Protein-ligand complex]]
[[Category: Transferase]]

Latest revision as of 11:03, 1 March 2024

The structure of the S. aureus DnaG RNA Polymerase Domain bound to CTP and Manganese

4ee1, resolution 2.02Å

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