4l00: Difference between revisions

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{{STRUCTURE_4l00|  PDB=4l00  |  SCENE=  }}
===Crystal structure of the apo Jak1 pseudokinase domain===
{{ABSTRACT_PUBMED_24013208}}


==Function==
==Crystal structure of the apo Jak1 pseudokinase domain==
[[http://www.uniprot.org/uniprot/JAK1_HUMAN JAK1_HUMAN]] Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.  
<StructureSection load='4l00' size='340' side='right'caption='[[4l00]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4l00]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L00 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4L00 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4l00 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l00 OCA], [https://pdbe.org/4l00 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4l00 RCSB], [https://www.ebi.ac.uk/pdbsum/4l00 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4l00 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/JAK1_HUMAN JAK1_HUMAN] Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.


==About this Structure==
==See Also==
[[4l00]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L00 OCA].
*[[Janus kinase 3D structures|Janus kinase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:024013208</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Eck MJ]]
[[Category: Eck, M J.]]
[[Category: Toms AV]]
[[Category: Toms, A V.]]
[[Category: Kinase domain fold]]
[[Category: Regulatory]]
[[Category: Transferase]]

Latest revision as of 12:16, 1 March 2024

Crystal structure of the apo Jak1 pseudokinase domain

4l00, resolution 1.80Å

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