4ok0: Difference between revisions
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== | ==Crystal structure of putative nucleotidyltransferase from H. pylori== | ||
[[4ok0]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OK0 OCA]. | <StructureSection load='4ok0' size='340' side='right'caption='[[4ok0]], [[Resolution|resolution]] 2.17Å' scene=''> | ||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4ok0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_J99 Helicobacter pylori J99]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OK0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OK0 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.17Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ok0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ok0 OCA], [https://pdbe.org/4ok0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ok0 RCSB], [https://www.ebi.ac.uk/pdbsum/4ok0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ok0 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/Q9ZKK2_HELPJ Q9ZKK2_HELPJ] | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
The jhp0933 gene in the plasticity region of Helicobacter pylori J99 encodes a hypothetical protein (JHP933), which may play some roles in pathogenesis. Here, we have determined the crystal structure of JHP933 at 2.17 A. It represents the first crystal structure of the DUF1814 protein family. JHP933 consists of two domains: an N-terminal domain of the nucleotidyltransferase (NTase) fold and a C-terminal helix bundle domain. A highly positively-charged surface patch exists adjacent to the putative NTP binding site. Structural similarity of JHP933 to known NTases is very remote, suggesting that it may function as a novel nucleotidyltransferase. (c) Proteins 2014;. (c) 2014 Wiley Periodicals, Inc. | |||
Crystal structure of JHP933 from Helicobacter pylori J99 shows two-domain architecture with a DUF1814 family nucleotidyltransferase domain and a helical bundle domain.,Yoon JY, Lee SJ, Kim DJ, Lee BJ, Yang JK, Suh SW Proteins. 2014 Mar 27. doi: 10.1002/prot.24572. PMID:24677396<ref>PMID:24677396</ref> | |||
<ref | |||
[[Category: | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
[[Category: | </div> | ||
[[Category: | <div class="pdbe-citations 4ok0" style="background-color:#fffaf0;"></div> | ||
[[Category: | == References == | ||
[[Category: | <references/> | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: Helicobacter pylori J99]] | |||
[[Category: Large Structures]] | |||
[[Category: Lee B]] | |||
[[Category: Lee SJ]] | |||
[[Category: Suh SW]] | |||
[[Category: Yang JK]] | |||
[[Category: Yoon JY]] | |||
Latest revision as of 19:24, 29 May 2024
Crystal structure of putative nucleotidyltransferase from H. pylori
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