4rco: Difference between revisions
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New page: '''Unreleased structure''' The entry 4rco is ON HOLD Authors: Minasov, G., Nocadello, S., Shuvalova, L., Filippova, E., Halavaty, A., Dubrovska, I., Flores, K., Bagnoli, F., Falugi, F.,... |
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==1.9 Angstrom Crystal Structure of Superantigen-like Protein, Exotoxin from Staphylococcus aureus, in Complex with Sialyl-LewisX.== | |||
<StructureSection load='4rco' size='340' side='right'caption='[[4rco]], [[Resolution|resolution]] 1.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4rco]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_NCTC_8325 Staphylococcus aureus subsp. aureus NCTC 8325]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RCO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RCO FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene>, <scene name='pdbligand=PRD_900122:Sialyl-Lewis+X+antigen,+alpha+anomer'>PRD_900122</scene>, <scene name='pdbligand=SIA:O-SIALIC+ACID'>SIA</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rco FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rco OCA], [https://pdbe.org/4rco PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rco RCSB], [https://www.ebi.ac.uk/pdbsum/4rco PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rco ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SSL4_STAA8 SSL4_STAA8] Secreted protein that plays a role in immune innate response inhibition by interfering with host TLR2-mediated pathway.<ref>PMID:22714643</ref> <ref>PMID:28858870</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Staphylococcus aureus subsp. aureus NCTC 8325]] | |||
[[Category: Anderson WF]] | |||
[[Category: Bagnoli F]] | |||
[[Category: Bottomley M]] | |||
[[Category: Dubrovska I]] | |||
[[Category: Falugi F]] | |||
[[Category: Filippova E]] | |||
[[Category: Flores K]] | |||
[[Category: Grandi G]] | |||
[[Category: Halavaty A]] | |||
[[Category: Minasov G]] | |||
[[Category: Nocadello S]] | |||
[[Category: Shuvalova L]] | |||
Latest revision as of 17:48, 20 September 2023
1.9 Angstrom Crystal Structure of Superantigen-like Protein, Exotoxin from Staphylococcus aureus, in Complex with Sialyl-LewisX.
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