3gd6: Difference between revisions

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==Crystal structure of divergent enolase from Oceanobacillus iheyensis complexed with phosphate==
==Crystal structure of divergent enolase from Oceanobacillus iheyensis complexed with phosphate==
<StructureSection load='3gd6' size='340' side='right' caption='[[3gd6]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='3gd6' size='340' side='right'caption='[[3gd6]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3gd6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Oceanobacillus_iheyensis_hte831 Oceanobacillus iheyensis hte831]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GD6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GD6 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3gd6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oceanobacillus_iheyensis_HTE831 Oceanobacillus iheyensis HTE831]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GD6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GD6 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2oqy|2oqy]], [[3fyy|3fyy]], [[3es7|3es7]], [[3es8|3es8]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">OB2843 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=221109 Oceanobacillus iheyensis HTE831])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gd6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gd6 OCA], [https://pdbe.org/3gd6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gd6 RCSB], [https://www.ebi.ac.uk/pdbsum/3gd6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gd6 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gd6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gd6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gd6 RCSB], [http://www.ebi.ac.uk/pdbsum/3gd6 PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/Q8EMJ9_OCEIH Q8EMJ9_OCEIH]] Catalyzes the regioselective dehydration of galactarate into 2-keto-D-threo-4,5-dihydroxyadipate ((2S,3R)-dihydroxy-5-oxohexanedioate). Is not active on other acid sugars.  
[https://www.uniprot.org/uniprot/GALRD_OCEIH GALRD_OCEIH] Catalyzes the regioselective dehydration of galactarate into 2-keto-D-threo-4,5-dihydroxyadipate ((2S,3R)-dihydroxy-5-oxohexanedioate). Is not active on other acid sugars.<ref>PMID:19883118</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gd/3gd6_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gd/3gd6_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3gd6 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Enolase 3D structures|Enolase 3D structures]]
*[[Muconate cycloisomerase|Muconate cycloisomerase]]
*[[Muconate cycloisomerase|Muconate cycloisomerase]]
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Oceanobacillus iheyensis hte831]]
[[Category: Large Structures]]
[[Category: Almo, S C]]
[[Category: Oceanobacillus iheyensis HTE831]]
[[Category: Burley, S K]]
[[Category: Almo SC]]
[[Category: Fedorov, A A]]
[[Category: Burley SK]]
[[Category: Fedorov, E V]]
[[Category: Fedorov AA]]
[[Category: Gerlt, J A]]
[[Category: Fedorov EV]]
[[Category: Structural genomic]]
[[Category: Gerlt JA]]
[[Category: Sauder, J M]]
[[Category: Sauder JM]]
[[Category: Divergent enolase]]
[[Category: Isomerase]]
[[Category: Lyase]]
[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
[[Category: PSI, Protein structure initiative]]
[[Category: Target 9375a]]

Latest revision as of 07:03, 6 September 2023

Crystal structure of divergent enolase from Oceanobacillus iheyensis complexed with phosphate

3gd6, resolution 1.60Å

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