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==Structure of a domain from the type IV pilus biogenesis lipoprotein PilP, from Pseudomonas aeruginosa==
==Structure of a domain from the type IV pilus biogenesis lipoprotein PilP, from Pseudomonas aeruginosa==
<StructureSection load='2y4y' size='340' side='right' caption='[[2y4y]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='2y4y' size='340' side='right'caption='[[2y4y]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2y4y]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y4Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y4Y FirstGlance]. <br>
<table><tr><td colspan='2'>[[2y4y]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y4Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y4Y FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2y4x|2y4x]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y4y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y4y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y4y RCSB], [http://www.ebi.ac.uk/pdbsum/2y4y PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y4y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y4y OCA], [https://pdbe.org/2y4y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y4y RCSB], [https://www.ebi.ac.uk/pdbsum/2y4y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y4y ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PILP_PSEAE PILP_PSEAE] Inner membrane component of the type IV (T4S) secretion system that plays a role in surface and host cell adhesion, colonization, biofilm maturation, virulence, and twitching, a form of surface-associated motility. PilN/PilO heterodimers form the foundation of the inner-membrane PilM/PilN/PilO/PilP complex which plays an essential role in the assembly of a functional T4 pilus (PubMed:19857645). PilP connects PilO to the secretin PilQ. In turn, the PilM/PilN/PilO/PilP/PilQ complex facilitates transit of the pilus through the periplasm and clamps the pilus in the cell envelope (PubMed:23457250).<ref>PMID:19857645</ref> <ref>PMID:23457250</ref>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Pseudomonas aeruginosa pao1]]
[[Category: Large Structures]]
[[Category: Berry, J]]
[[Category: Pseudomonas aeruginosa PAO1]]
[[Category: Derrick, J P]]
[[Category: Berry J]]
[[Category: Biosynthetic protein]]
[[Category: Derrick JP]]
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