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[[Image:2yzl.jpg|left|200px]]


{{Structure
==Crystal structure of phosphoribosylaminoimidazole-succinocarboxamide synthase with ADP from Methanocaldococcus jannaschii==
|PDB= 2yzl |SIZE=350|CAPTION= <scene name='initialview01'>2yzl</scene>, resolution 2.20&Aring;
<StructureSection load='2yzl' size='340' side='right'caption='[[2yzl]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=ADP:ADENOSINE-5'-DIPHOSPHATE'>ADP</scene>
<table><tr><td colspan='2'>[[2yzl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YZL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YZL FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/Phosphoribosylaminoimidazolesuccinocarboxamide_synthase Phosphoribosylaminoimidazolesuccinocarboxamide synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.6 6.3.2.6]  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yzl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yzl OCA], [https://pdbe.org/2yzl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yzl RCSB], [https://www.ebi.ac.uk/pdbsum/2yzl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yzl ProSAT], [https://www.topsan.org/Proteins/RSGI/2yzl TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PUR7_METJA PUR7_METJA]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yz/2yzl_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2yzl ConSurf].
<div style="clear:both"></div>


'''Crystal structure of phosphoribosylaminoimidazole-succinocarboxamide synthase with ADP from Methanocaldococcus jannaschii'''
==See Also==
 
*[[SAICAR synthetase|SAICAR synthetase]]
 
__TOC__
==About this Structure==
</StructureSection>
2YZL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YZL OCA].
[[Category: Large Structures]]
[[Category: Methanocaldococcus jannaschii]]
[[Category: Methanocaldococcus jannaschii]]
[[Category: Phosphoribosylaminoimidazolesuccinocarboxamide synthase]]
[[Category: Baba S]]
[[Category: Single protein]]
[[Category: Fukui K]]
[[Category: Baba, S.]]
[[Category: Kanagawa M]]
[[Category: Fukui, K.]]
[[Category: Kawai G]]
[[Category: Kanagawa, M.]]
[[Category: Kuramitsu S]]
[[Category: Kawai, G.]]
[[Category: Sampei G]]
[[Category: Kuramitsu, S.]]
[[Category: Yokoyama S]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Sampei, G.]]
[[Category: Yokoyama, S.]]
[[Category: ADP]]
[[Category: SO4]]
[[Category: 2-layer sandwich]]
[[Category: ligase]]
[[Category: national project on protein structural and functional analyse]]
[[Category: nppsfa]]
[[Category: purine biosynthesis]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:50:33 2008''

Latest revision as of 09:13, 25 October 2023

Crystal structure of phosphoribosylaminoimidazole-succinocarboxamide synthase with ADP from Methanocaldococcus jannaschii

2yzl, resolution 2.20Å

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