5c5c: Difference between revisions
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New page: '''Unreleased structure''' The entry 5c5c is ON HOLD Authors: Dong, A., Dobrovetsky, E., Hutchinson, A., Tempel, W., Bountra, C., Edwards, A.M., Arrowsmith, C.H., Structural Genomics Co... |
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==Human metabotropic glutamate receptor 7, extracellular ligand binding domain== | |||
<StructureSection load='5c5c' size='340' side='right'caption='[[5c5c]], [[Resolution|resolution]] 1.86Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5c5c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C5C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5C5C FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.862Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5c5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c5c OCA], [https://pdbe.org/5c5c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5c5c RCSB], [https://www.ebi.ac.uk/pdbsum/5c5c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5c5c ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/GRM7_HUMAN GRM7_HUMAN] G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.<ref>PMID:9473604</ref> | |||
==See Also== | |||
*[[Metabotropic glutamate receptor 3D structures|Metabotropic glutamate receptor 3D structures]] | |||
== References == | |||
[[Category: | <references/> | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Arrowsmith CH]] | ||
[[Category: | [[Category: Bountra C]] | ||
[[Category: | [[Category: Dobrovetsky E]] | ||
[[Category: | [[Category: Dong A]] | ||
[[Category: Edwards AM]] | |||
[[Category: Hutchinson A]] | |||
[[Category: Tempel W]] | |||
Latest revision as of 03:55, 21 November 2024
Human metabotropic glutamate receptor 7, extracellular ligand binding domain
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