3jb9: Difference between revisions
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==Cryo-EM structure of the yeast spliceosome at 3.6 angstrom resolution== | |||
<SX load='3jb9' size='340' side='right' viewer='molstar' caption='[[3jb9]], [[Resolution|resolution]] 3.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3jb9]] is a 17 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe] and [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JB9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JB9 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.6Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jb9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jb9 OCA], [https://pdbe.org/3jb9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jb9 RCSB], [https://www.ebi.ac.uk/pdbsum/3jb9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jb9 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SPP42_SCHPO SPP42_SCHPO] Involved in pre-mRNA splicing. May be involved in endoplasmic reticulum-associated protein degradation (ERAD) and required for growth at low and high temperatures (By similarity). Required for pre-spliceosome formation, which is the first step of pre-mRNA splicing. This protein is associated with snRNP U5. Has a role in branch site-3' splice site selection. Associates with the branch site-3' splice 3'-exon region.<ref>PMID:16133344</ref> | |||
==See Also== | |||
*[[Helicase 3D structures|Helicase 3D structures]] | |||
*[[Pre-mRNA splicing factors 3D structures|Pre-mRNA splicing factors 3D structures]] | |||
[[Category: | *[[Sm-like protein 3D structures|Sm-like protein 3D structures]] | ||
[[Category: Yan | == References == | ||
<references/> | |||
__TOC__ | |||
</SX> | |||
[[Category: Large Structures]] | |||
[[Category: Schizosaccharomyces pombe]] | |||
[[Category: Schizosaccharomyces pombe 972h-]] | |||
[[Category: Hang J]] | |||
[[Category: Huang M]] | |||
[[Category: Shi Y]] | |||
[[Category: Wan R]] | |||
[[Category: Wong C]] | |||
[[Category: Yan C]] | |||
Latest revision as of 08:42, 7 February 2024
Cryo-EM structure of the yeast spliceosome at 3.6 angstrom resolution
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