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| | <StructureSection load='1uku' size='350' side='right' caption='CutA1 complex with copper (PDB entry [[1uku]])' scene='50/508403/Cv/1'> |
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| <StructureSection load='1uku' size='350' side='right' caption='CutA1 complex with copper (PDB entry [[1uku]])' scene=''>
| | '''CutA1''' or '''periplasmic divalent cation tolerance protein''' is involved in copper tolerance in ''E. coli''. In mammals it is implicated in the anchoring of acetylcholinesterase in the neural cell membrane. The thermostability of CutA1 from ''Pyrococcus horikoshii'' is extremely high.<ref>PMID:14706845</ref> See [[Divalent cation tolerant protein CUTA from Homo sapiens O60888]]. |
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| '''CutA1''' is involved in copper tolerance in ''E. coli''. In mammals it is implicated in the anchoring of acetylcholinesterase in the neural cell membrane. The thermostability of CutA1 from ''Pyrococcus horikoshii'' is extremely high.<ref>PMID:14706845</ref>
| | == Structural highlights == |
| </StructureSection>
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| ==3D structures of CutA1== | |
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| Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
| | The <scene name='50/508403/Cv/2'>copper ion is bound to Asp and Lys residues</scene>. |
| {{#tree:id=OrganizedByTopic|openlevels=0|
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| *CutA1
| | ==3D structures of CutA1== |
| | [[CutA1 3D structures]] |
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| **[[1kr4]], [[1o5j]], [[1vhf]] – TmCutA – ''Thermotoga maritima''<br />
| | </StructureSection> |
| **[[1nza]], [[1v6h]] – CutA – ''Thermus thermophilus''<br />
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| **[[1p1l]] – CutA – ''Archaeoglobus fulgidus''<br />
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| **[[1naq]] – EcCutA – ''Escherichia coli''<br />
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| **[[3aa8]], [[3aa9]], [[3ah6]] - EcCutA (mutant)<br />
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| **[[1osc]] – CutA – rat<br />
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| **[[1xk8]] – CutA – human<br />
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| **[[2zom]] - CutA - rice<br />
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| **[[1j2v]] – PhCutA – ''Pyrococcus horikoshii''<br />
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| **[[3gsd]] - CutA – ''Yersinia pestis''<br />
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| **[[3opk]] - CutA – ''Salmonella enterica''<br />
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| **[[2e66]] - PhCutA (mutant)<br />
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| **[[3ahp]] – CutA – ''Shewanella''<br />
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| **[[4iyq]] – CutA – ''Ehrlichia chaffeensis''<br />
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| **[[4e98]] – CutA – ''Cryptosporidium parvum''<br />
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| *CutA1 binary complex
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| **[[1uku]], [[1v99]] – PhCutA + Cu<br />
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| **[[1v9b]] - PhCutA + Co<br />
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| **[[1umj]] - PhCutA + guanidine
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| }}
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| == References == | | == References == |
| <references/> | | <references/> |
| [[Category:Topic Page]] | | [[Category:Topic Page]] |
