4ycm: Difference between revisions
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==Crystal structure of the calcium pump with bound marine macrolide BLS== | ==Crystal structure of the calcium pump with bound marine macrolide BLS== | ||
<StructureSection load='4ycm' size='340' side='right' caption='[[4ycm]], [[Resolution|resolution]] 3.20Å' scene=''> | <StructureSection load='4ycm' size='340' side='right'caption='[[4ycm]], [[Resolution|resolution]] 3.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4ycm]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4ycm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YCM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YCM FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7BS:(4S,5E,8S,9E,11S,13E,15E,18R)-8-METHOXY-9,11-DIMETHYL-18-[(1Z,4E)-2-METHYLHEXA-1,4-DIEN-1-YL]-2-OXOOXACYCLOOCTADECA-5,9,13,15-TETRAEN-4-YL+3-O-METHYL-BETA-D-GLUCOPYRANOSIDE'>7BS</scene>, <scene name='pdbligand= | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7BS:(4S,5E,8S,9E,11S,13E,15E,18R)-8-METHOXY-9,11-DIMETHYL-18-[(1Z,4E)-2-METHYLHEXA-1,4-DIEN-1-YL]-2-OXOOXACYCLOOCTADECA-5,9,13,15-TETRAEN-4-YL+3-O-METHYL-BETA-D-GLUCOPYRANOSIDE'>7BS</scene>, <scene name='pdbligand=AME:N-ACETYLMETHIONINE'>AME</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PTY:PHOSPHATIDYLETHANOLAMINE'>PTY</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ycm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ycm OCA], [https://pdbe.org/4ycm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ycm RCSB], [https://www.ebi.ac.uk/pdbsum/4ycm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ycm ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/AT2A1_RABIT AT2A1_RABIT] This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 20: | Line 19: | ||
</div> | </div> | ||
<div class="pdbe-citations 4ycm" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4ycm" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[ATPase 3D structures|ATPase 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Oryctolagus cuniculus]] | [[Category: Oryctolagus cuniculus]] | ||
[[Category: Morita | [[Category: Morita M]] | ||
[[Category: Ogawa | [[Category: Ogawa H]] | ||
[[Category: Ohno | [[Category: Ohno O]] | ||
[[Category: Suenaga | [[Category: Suenaga K]] | ||
[[Category: Toyoshima | [[Category: Toyoshima C]] | ||
[[Category: Yamori | [[Category: Yamori T]] | ||
Latest revision as of 08:37, 9 April 2025
Crystal structure of the calcium pump with bound marine macrolide BLS
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