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[[Image:1h1k.gif|left|200px]]


{{Structure
==THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA==
|PDB= 1h1k |SIZE=350|CAPTION= <scene name='initialview01'>1h1k</scene>, resolution 10.&Aring;
<StructureSection load='1h1k' size='340' side='right'caption='[[1h1k]], [[Resolution|resolution]] 10.00&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=A:ADENOSINE-5&#39;-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=U:URIDINE-5&#39;-MONOPHOSPHATE'>U</scene>
<table><tr><td colspan='2'>[[1h1k]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bluetongue_virus Bluetongue virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H1K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1H1K FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 10&#8491;</td></tr>
|GENE=  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1h1k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h1k OCA], [https://pdbe.org/1h1k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1h1k RCSB], [https://www.ebi.ac.uk/pdbsum/1h1k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1h1k ProSAT]</span></td></tr>
|DOMAIN=
</table>
|RELATEDENTRY=
<div style="background-color:#fffaf0;">
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h1k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h1k OCA], [http://www.ebi.ac.uk/pdbsum/1h1k PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1h1k RCSB]</span>
== Publication Abstract from PubMed ==
}}
 
'''THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA'''
 
 
==Overview==
Double-stranded RNA (dsRNA) viruses conceal their genome from the host to avoid triggering unfavorable cellular responses. The crystal structure of the core of one such virus, bluetongue virus, reveals an outer surface festooned with dsRNA. This may represent a deliberate strategy to sequester dsRNA released from damaged particles to prevent host cell shutoff.
Double-stranded RNA (dsRNA) viruses conceal their genome from the host to avoid triggering unfavorable cellular responses. The crystal structure of the core of one such virus, bluetongue virus, reveals an outer surface festooned with dsRNA. This may represent a deliberate strategy to sequester dsRNA released from damaged particles to prevent host cell shutoff.


==About this Structure==
The core of bluetongue virus binds double-stranded RNA.,Diprose JM, Grimes JM, Sutton GC, Burroughs JN, Meyer A, Maan S, Mertens PP, Stuart DI J Virol. 2002 Sep;76(18):9533-6. PMID:12186935<ref>PMID:12186935</ref>
1H1K is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bluetongue_virus Bluetongue virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H1K OCA].


==Reference==
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
The core of bluetongue virus binds double-stranded RNA., Diprose JM, Grimes JM, Sutton GC, Burroughs JN, Meyer A, Maan S, Mertens PP, Stuart DI, J Virol. 2002 Sep;76(18):9533-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12186935 12186935]
</div>
<div class="pdbe-citations 1h1k" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Bluetongue virus]]
[[Category: Bluetongue virus]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Burroughs, J N.]]
[[Category: Burroughs JN]]
[[Category: Diprose, J M.]]
[[Category: Diprose JM]]
[[Category: Grimes, J M.]]
[[Category: Grimes JM]]
[[Category: Maan, S.]]
[[Category: Maan S]]
[[Category: Mertens, P P.C.]]
[[Category: Mertens PPC]]
[[Category: Meyer, A.]]
[[Category: Meyer A]]
[[Category: Stuart, D I.]]
[[Category: Stuart DI]]
[[Category: Sutton, G.]]
[[Category: Sutton GC]]
[[Category: virus,viral protein,rna]]
 
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Retrieved from "https://proteopedia.org/1h1k"