5khs: Difference between revisions
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==Crystal structures of the Burkholderia multivorans hopanoid transporter HpnN== | |||
<StructureSection load='5khs' size='340' side='right'caption='[[5khs]], [[Resolution|resolution]] 3.76Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5khs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_multivorans Burkholderia multivorans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KHS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5KHS FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.758Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5khs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5khs OCA], [https://pdbe.org/5khs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5khs RCSB], [https://www.ebi.ac.uk/pdbsum/5khs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5khs ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Su | == Function == | ||
[https://www.uniprot.org/uniprot/HPNN_BURM1 HPNN_BURM1] Essential for hopanoid transport from the cytoplasmic to the outer membrane (PubMed:28584102). Is capable of shuttling hopanoid lipids from the inner membrane to the periplasm, where they probably spontaneously insert to the inner leaflet of the outer membrane, strengthening the cell envelope (PubMed:28584102). May be a proton-motive-force (PMF)-dependent transporter (PubMed:28584102). Is critical for multidrug resistance and cell wall remodeling in Burkholderia (PubMed:28584102).<ref>PMID:28584102</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Burkholderia multivorans]] | |||
[[Category: Large Structures]] | |||
[[Category: Su C-C]] | |||
[[Category: Yu EW]] | |||
Latest revision as of 12:40, 6 March 2024
Crystal structures of the Burkholderia multivorans hopanoid transporter HpnN
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