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==Crystal structure of nitric oxide reductase from Pseudomonas aeruginosa in complex with antibody fragment==
==Crystal structure of nitric oxide reductase from Pseudomonas aeruginosa in complex with antibody fragment==
<StructureSection load='3o0r' size='340' side='right' caption='[[3o0r]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='3o0r' size='340' side='right'caption='[[3o0r]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3o0r]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O0R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3O0R FirstGlance]. <br>
<table><tr><td colspan='2'>[[3o0r]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O0R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3O0R FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=O:OXYGEN+ATOM'>O</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nitric-oxide_reductase_(cytochrome_c) Nitric-oxide reductase (cytochrome c)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.7.2.5 1.7.2.5] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=O:OXYGEN+ATOM'>O</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3o0r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o0r OCA], [http://pdbe.org/3o0r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3o0r RCSB], [http://www.ebi.ac.uk/pdbsum/3o0r PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3o0r ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3o0r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o0r OCA], [https://pdbe.org/3o0r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3o0r RCSB], [https://www.ebi.ac.uk/pdbsum/3o0r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3o0r ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/NORC_PSEAE NORC_PSEAE]] Component of the anaerobic respiratory chain that transforms nitrate to dinitrogen (denitrification). [[http://www.uniprot.org/uniprot/NORB_PSEAE NORB_PSEAE]] Component of the anaerobic respiratory chain that transforms nitrate to dinitrogen (denitrification). NorB is the catalytic subunit of the enzyme complex. Shows proton pump activity across the membrane in denitrifying bacterial cells. The mononitrogen reduction is probably coupled to electron transport phosphorylation (By similarity).  
[https://www.uniprot.org/uniprot/NORB_PSEAE NORB_PSEAE] Component of the anaerobic respiratory chain that transforms nitrate to dinitrogen (denitrification). NorB is the catalytic subunit of the enzyme complex. Shows proton pump activity across the membrane in denitrifying bacterial cells. The mononitrogen reduction is probably coupled to electron transport phosphorylation (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Nitric reductase|Nitric reductase]]
*[[Antibody 3D structures|Antibody 3D structures]]
*[[3D structures of antibody|3D structures of antibody]]
*[[Cytochrome c nitrite reductase|Cytochrome c nitrite reductase]]
*[[3D structures of non-human antibody|3D structures of non-human antibody]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa PAO1]]
[[Category: Fukumori, Y]]
[[Category: Fukumori Y]]
[[Category: Hino, T]]
[[Category: Hino T]]
[[Category: Iwata, S]]
[[Category: Iwata S]]
[[Category: Matsumoto, Y]]
[[Category: Matsumoto Y]]
[[Category: Murata, T]]
[[Category: Murata T]]
[[Category: Nagano, S]]
[[Category: Nagano S]]
[[Category: Shiro, Y]]
[[Category: Shiro Y]]
[[Category: Sugimoto, H]]
[[Category: Sugimoto H]]
[[Category: Cytoplasmic membrane]]
[[Category: Electron transport]]
[[Category: Heme]]
[[Category: Immune system-oxidoreductase complex]]
[[Category: Iron]]
[[Category: Membrane]]
[[Category: Oxidoreductase]]

Latest revision as of 09:29, 30 October 2024

Crystal structure of nitric oxide reductase from Pseudomonas aeruginosa in complex with antibody fragment

3o0r, resolution 2.70Å

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