Cytochrome c nitrite reductase

spinqualitylabelsall models Cytochrome c nitrite reductase with 5 heme groups complex with NO2, acetate, Ca+2 ion (green) and Y+3 ion (cyan) (PDB code 2e80) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Cytochrome c nitrite reductase or cytochrome c552 (ccNiR) catalyzes the reduction of nitrite to ammonia as one of the key steps in the nitrogen cycle where it participates in the anaerobic energy metabolism of dissimilatory nitrate ammonification. See also Hemeproteins: Cytochrome c Nitrite Reductase. Structural highlights Cytochrome c nitrite reductase with 5 heme groups (PDB code 2e80). In the Wolinella succinogenes ccNiR structure the substrate NO2 binds to the Fe+3 atom of the heme group and makes hydrogen bonds to side chains of residues R114 and H277. NO2 hydrogen bonds via water molecules also with other residues. Water molecules are shown as red spheres. Rare-earth element Yttrium ion binding site.

3D structures of cytochrome c nitrite reductase

Updated on 02-March-2025

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• Cytochrome c nitrite reductase
  • Hemeproteins: Cytochrome c Nitrite Reductase – ccNiR – Sulfurospirilum deleyianum
    
  • 2e80, 1fs8, 1fs9, ]]3bnf]] – WsccNiR – Wolinella succinogenes
    
  • 3bng, 3bnj – WsccNiR (mutant)
    
  • 1gu6, 2rdz, 3l1t, 3tor – EcccNiR – Eschericia coli<br />
  • 2rf7, 4wjy – EcccNiR (mutant)
    
  • 6p73, 9cuf – SoccNiR – Shewanella oneidensis
    
  • 3ubr – SoccNiR - Laue
    
  • 2j7a – DvccNiR – Desulfovibrio vulgaris
    
  • 1oah – ccNiR – Desulfovibrio desulfuricans
    
  • 6v0a – ccNiR – Geobacter lovleyi
    
• Cytochrome c nitrite reductase complex
  • 2e80 – WsccNiR + NO2
    
  • 3bnh – WsccNiR (mutant) + NO2
    
  • 2e81 – WsccNiR + hydroxylamine
    
  • 2vr0 – DvccNiR catalytic subunit + NRFH + quinolone derivative
    
• Eight-heme nitrite reductase
  • 2ot4, 2zo5, 3f29, 3gm6, 3mmo, 3ttb, 3uu9, 3fo3, 3lg1, 3lgq, 3sce, 4l3x, 4l3y, 4l3z, 4q0t, 4q17, 4q1o, 4q4u, 4q5b, 4q5c – TnccNiR – Thioalkalivibrio nitratireducens
    
  • 7o9u – TnccNiR – NMR
    
  • 3owm, 3s7w – TnccNiR + hydroxylamine
    
  • 3d1i, 3rkh – TnccNiR + NO2
    
  • 8rv0 – ccNiR + NO2 + NO – Trichlorobacter ammonificans
    
• Heme-containing nitrite reductase - (Cytochrome C-552)
  • 1aof, 1qks, 1hj4, 1hj5, 1h9x, 1hcm - PpNIR – Paracoccus pantotrophus
    
  • 1gq1 - PpNIR (mutant)
    
  • 1nir, 1bl9, 1n15, 1n50, 1n90, 6rtd, 6rte, 6tpo, 6tsi – PaNIR – Pseudomonas aeruginosa
    
  • 1hzu - PaNIR (mutant)
    
  • 1qdb - NIR – Sulfurospirillum deleyianum
    
  • 1fs7, 1fs8 - WsNIR – Wolinella succinogenes
    
  • 3bng - WsNIR (mutant)
    
  • 1gu6, 2rdz, 3tor – EcNIR – Escherichia coli
    
  • 2rf7, 4wjy - EcNIR (mutant)
    
  • 2jo6 – EcNIR small subunit – NMR
    
  • 2jza - NIR small subunit – Pectobacterium atrosepticum - NMR
    
  • 1oah – NIR – Desulfovibrio desulfuricans
    
  • 2j7a - DvNIR – Desulfovibrio vulgaris
    
  • 2ot4, 3gm6, 3fo3, 3sce, 3uu9, 4q0t, 4q17, 4q1o, 4q4u, 4q5b, 4q5c - TnNIR – Thioalkalivibrio nitratireducens
    
  • 3m97 – PdNIR soluble domain – Paracoccus denitrificans
    
  • 2ai5 – HtNIR – Hydrogenophilus thermophilus – NMR
    
  • 2d0s, 1ynr, 3vym – HtNIR
    
  • 1ayg – NIR - Hydrogenobacter thermoluteolus – NMR
    
  • 1i6d, 1i6e, 1c7m – PdNIR functional domain – NMR
    
  • 1ql3, 1ql4 - PdNIR functional domain
    
  • 1dt1, 1qyz, 1r0q, 1c52, 3vnw – TtNIR – Thermus thermophilus
    
  • 2fwl – TtNIR + NIR oxidase subunit II
    
  • 1cno – NIR – Pseudomonas nautica
    
  • 3ubr, 6p73 – SoNIR – Shewanella oneidensis
    
  • 3sqx – TpNIR – Thioalkalivibrio paradoxus
    
  • 6v0a – NIR – Geobacter lovleyi
    
• Heme-containing nitrite reductase binary complex
  • 1dy7 - PpNIR + CO
    
  • 1hj3 - PpNIR + O2
    
  • 2e81 - WsNIR + NH2OH
    
  • 3bnf - WsNIR + sulfite
    
  • 2vr0 - DvNIR + HQNO inhibitor
    
  • 3ziy, 4ax3, 6fja, 6f1q – RpNIR + Cu – Ralstonia pickettii
    
  • 3ayf – NIR + Zn – Geobacillus stearothermophilus
    
  • 2yqb, 3zbm – RpNIR (mutant) + Cu
    
  • 3o0r – PaNIR + antibody
    
  • 5guw – PaNIR + nitric oxide reductase
    
  • 3sxq – TpNIR + Co
    
• Heme-containing nitrite reductase binary complex with cyanide
  • 1h9y - PpNIR + CN
    
  • 1gjq - PaNIR + CN
    
  • 1e2r - PdNIR+ CN
    
• Heme-containing nitrite reductase binary complex with nitric oxide
  • 1nno - PaNIR + NO
    
  • 1hzv - PaNIR (mutant) + NO
    
  • 1aom, 1aoq, 5ocb, 5ocf - PpNIR + NO + NO2
    
  • 5obo - PpNIR (mutant) + Cu + NO2
    
• Heme-containing nitrite reductase binary complex with nitrite
  • 2e80 - WsNIR + NO2
    
  • 3bnh - WsNIR (mutant) + NO
    
  • 3d1i, 3rkh, 3owm, 4l38, 4l3x, 4l3y, 4l3z - TnNIR + NO2
    
  • 6qwg - AcNIR + Cu + NO2
    
  • 6tfd - HdNIR + Cu + NO2
    
• Heme-containing nitrite reductase binary complex with azide
  • 2zo5 - TnNIR + N3
    
  • 3s7w - TnNIR + NO2 + N3
    
  • 1fs9 - WsNIR + N3
• Heme-containing nitrite reductase binary complex with sulfite
  • 3mmo - WsNIR + SO3
    
  • 3bnj - WsNIR (mutant) + SO3
    
  • 3lg1, 3lgq, 3f29, 3ttb - TnNIR + SO3
    
  • 3l1t - EcNIR + SO3
    

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