5t36: Difference between revisions
From Proteopedia
Jump to navigationJump to search
New page: '''Unreleased structure''' The entry 5t36 is ON HOLD Authors: Luz, J.G., Antonysamy, S., Partridge, K., Fisher, M. Description: Crystal structure of mPGES-1 bound to inhibitor [[Catego... |
No edit summary |
||
| (4 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Crystal structure of mPGES-1 bound to inhibitor== | |||
<StructureSection load='5t36' size='340' side='right'caption='[[5t36]], [[Resolution|resolution]] 1.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5t36]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T36 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5T36 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=755:4-CHLORO-2-[({(1S,2S)-2-[(2,2-DIMETHYLPROPANOYL)AMINO]CYCLOPENTYL}METHYL)AMINO]BENZOIC+ACID'>755</scene>, <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5t36 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t36 OCA], [https://pdbe.org/5t36 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5t36 RCSB], [https://www.ebi.ac.uk/pdbsum/5t36 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5t36 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PTGES_HUMAN PTGES_HUMAN] Catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2).<ref>PMID:18682561</ref> | |||
==See Also== | |||
*[[Prostaglandin E synthase|Prostaglandin E synthase]] | |||
== References == | |||
[[Category: | <references/> | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Antonysamy S]] | |||
[[Category: Fisher M]] | |||
[[Category: Luz JG]] | |||
[[Category: Partridge K]] | |||
Latest revision as of 14:18, 6 March 2024
Crystal structure of mPGES-1 bound to inhibitor
| ||||||||||||
