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==Crystal structure of monkey TLR7 in complex with loxoribine and polyU==
==Crystal structure of monkey TLR7 in complex with loxoribine and polyU==
<StructureSection load='5gmg' size='340' side='right' caption='[[5gmg]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='5gmg' size='340' side='right'caption='[[5gmg]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5gmg]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GMG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5GMG FirstGlance]. <br>
<table><tr><td colspan='2'>[[5gmg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Macaca_mulatta Macaca mulatta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GMG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5GMG FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SDL:2-AZANYL-9-[(2~{R},3~{R},4~{S},5~{R})-5-(HYDROXYMETHYL)-3,4-BIS(OXIDANYL)OXOLAN-2-YL]-7-PROP-2-ENYL-1~{H}-PURINE-6,8-DIONE'>SDL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5gmf|5gmf]], [[5gmh|5gmh]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SDL:2-AZANYL-9-[(2~{R},3~{R},4~{S},5~{R})-5-(HYDROXYMETHYL)-3,4-BIS(OXIDANYL)OXOLAN-2-YL]-7-PROP-2-ENYL-1~{H}-PURINE-6,8-DIONE'>SDL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5gmg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gmg OCA], [http://pdbe.org/5gmg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5gmg RCSB], [http://www.ebi.ac.uk/pdbsum/5gmg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5gmg ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5gmg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gmg OCA], [https://pdbe.org/5gmg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5gmg RCSB], [https://www.ebi.ac.uk/pdbsum/5gmg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5gmg ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/B3Y653_MACMU B3Y653_MACMU]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5gmg" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5gmg" style="background-color:#fffaf0;"></div>
==See Also==
*[[Toll-like Receptor 3D structures|Toll-like Receptor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ohto, U]]
[[Category: Homo sapiens]]
[[Category: Shimizu, T]]
[[Category: Large Structures]]
[[Category: Zhang, Z]]
[[Category: Macaca mulatta]]
[[Category: Immune system]]
[[Category: Ohto U]]
[[Category: Immune system-rna complex]]
[[Category: Shimizu T]]
[[Category: Innate immunity]]
[[Category: Zhang Z]]
[[Category: Ssrna recogniton]]
[[Category: Tlr7]]

Latest revision as of 11:36, 2 August 2023

Crystal structure of monkey TLR7 in complex with loxoribine and polyU

5gmg, resolution 2.60Å

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