Apoptosis-inducing factor: Difference between revisions

Latest revision as of 09:56, 15 March 2018

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Human apoptosis-inducing factor complex with FAD, NAD and sulfate (PDB code 4bur)

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-<StructureSection load='4bur' size='340' side='right' caption='Human apoptosis-inducing factor complex with FAD, NAD and sulfate 9PDB code [[4bur]])' scene=''>
+<StructureSection load='' size='450' side='right' caption='Human apoptosis-inducing factor complex with FAD, NAD and sulfate (PDB code [[4bur]])' scene='74/749463/Cv/1'>
 == Function ==
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 == Structural highlights ==
+The AIF binding site contains the cofactor <scene name='74/749463/Cv/2'>FAD</scene> and 2 molecules of the reducing factor NADH<ref>PMID:24914854</ref>. Water molecules shown as red spheres.
+*<scene name='74/749463/Cv/3'>1st NADH binding site</scene>.
+*<scene name='74/749463/Cv/4'>2nd NADH binding site</scene>.
+*<scene name='74/749463/Cv/5'>FAD/1st molecule NADF tunnel</scene>.
+*<scene name='74/749463/Cv/6'>2nd NADH binding site in surface representation</scene>.
 </StructureSection>
-==3D structures of apoptosis-inducing factor==
+==3D structures of apoptosis-inducing factor see CED-8 in [[Cell death protein]]==
-Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
-[[4bv6]], [[4lii]], [[1m6i]] – hAIF – human <br />
-[[5fmh]], [[5kvh]], [[5kvi]], [[5fs6]], [[5fs7]], [[5fs8]], [[4fdc]] – hAIF (mutant)  <br />
-[[4bur]] – hAIF + NAD <br />
-[[3gd3]], [[1gv4]] – mAIF – mouse <br />
-[[3gd4]] – mAIF + NAD <br />
 == References ==
 <references/>
+[[Category:Topic Page]]