4xk4: Difference between revisions
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==E. coli transcriptional regulator RUTR with dihydrouracil== | ==E. coli transcriptional regulator RUTR with dihydrouracil== | ||
<StructureSection load='4xk4' size='340' side='right' caption='[[4xk4]], [[Resolution|resolution]] 2.27Å' scene=''> | <StructureSection load='4xk4' size='340' side='right'caption='[[4xk4]], [[Resolution|resolution]] 2.27Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4xk4]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XK4 OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[4xk4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XK4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XK4 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.27Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DUC:DIHYDROPYRIMIDINE-2,4(1H,3H)-DIONE'>DUC</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xk4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xk4 OCA], [https://pdbe.org/4xk4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xk4 RCSB], [https://www.ebi.ac.uk/pdbsum/4xk4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xk4 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/RUTR_ECOLI RUTR_ECOLI] Master transcription regulator which represses the degradation of pyrimidines (rutABCDEFG) and purines (gcl operon) for maintenance of metabolic balance between pyrimidines and purines. It also regulates the synthesis of pyrimidine nucleotides and arginine from glutamine (carAB) and the supply of glutamate (gadABWX).<ref>PMID:16540542</ref> <ref>PMID:17919280</ref> | ||
==See Also== | |||
*[[Tetracycline repressor protein 3D structures|Tetracycline repressor protein 3D structures]] | |||
*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Escherichia coli K-12]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Almo SC]] | ||
[[Category: | [[Category: Cooper DR]] | ||
[[Category: | [[Category: Grabowski M]] | ||
[[Category: | [[Category: Minor W]] | ||
[[Category: | [[Category: Shabalin IG]] | ||
[[Category: | [[Category: Shumilin IA]] | ||
Latest revision as of 07:46, 27 September 2023
E. coli transcriptional regulator RUTR with dihydrouracil
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