1tk2: Difference between revisions
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==Crystal Structure of the Complex formed between Alkaline Proteinase Savinase and Gramicidin S at 1.5A Resolution== | |||
<StructureSection load='1tk2' size='340' side='right'caption='[[1tk2]], [[Resolution|resolution]] 1.54Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1tk2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Brevibacillus_brevis Brevibacillus brevis] and [https://en.wikipedia.org/wiki/Lederbergia_lenta Lederbergia lenta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TK2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TK2 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.54Å</td></tr> | |||
| | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DPN:D-PHENYLALANINE'>DPN</scene>, <scene name='pdbligand=ORN:L-ORNITHINE'>ORN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tk2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tk2 OCA], [https://pdbe.org/1tk2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tk2 RCSB], [https://www.ebi.ac.uk/pdbsum/1tk2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tk2 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SUBS_LEDLE SUBS_LEDLE] Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tk/1tk2_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tk2 ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[Gramicidin|Gramicidin]] | |||
*[[Subtilisin 3D structures|Subtilisin 3D structures]] | |||
== | __TOC__ | ||
</StructureSection> | |||
[[Category: | [[Category: Brevibacillus brevis]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Lederbergia lenta]] | ||
[[Category: Betzel | [[Category: Betzel C]] | ||
[[Category: Bhatt | [[Category: Bhatt VS]] | ||
[[Category: Brenner | [[Category: Brenner S]] | ||
[[Category: Kaur | [[Category: Kaur P]] | ||
[[Category: Klupsch | [[Category: Klupsch S]] | ||
[[Category: Singh | [[Category: Singh TP]] | ||
Latest revision as of 06:31, 23 August 2023
Crystal Structure of the Complex formed between Alkaline Proteinase Savinase and Gramicidin S at 1.5A Resolution
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