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==Crystal structure of nucleoside diphosphate kinase from Neisseria gonorrhoeae in complex with citrate==
==Crystal structure of nucleoside diphosphate kinase from Neisseria gonorrhoeae in complex with citrate==
<StructureSection load='5v6d' size='340' side='right' caption='[[5v6d]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
<StructureSection load='5v6d' size='340' side='right'caption='[[5v6d]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5v6d]] is a 16 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V6D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5V6D FirstGlance]. <br>
<table><tr><td colspan='2'>[[5v6d]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Neisseria_gonorrhoeae_NCCP11945 Neisseria gonorrhoeae NCCP11945]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V6D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5V6D FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nucleoside-diphosphate_kinase Nucleoside-diphosphate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.6 2.7.4.6] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5v6d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v6d OCA], [http://pdbe.org/5v6d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5v6d RCSB], [http://www.ebi.ac.uk/pdbsum/5v6d PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5v6d ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5v6d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v6d OCA], [https://pdbe.org/5v6d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5v6d RCSB], [https://www.ebi.ac.uk/pdbsum/5v6d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5v6d ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/NDK_NEIG2 NDK_NEIG2]] Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.  
[https://www.uniprot.org/uniprot/NDK_NEIG2 NDK_NEIG2] Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
 
==See Also==
*[[Nucleoside diphosphate kinase 3D structures|Nucleoside diphosphate kinase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Nucleoside-diphosphate kinase]]
[[Category: Large Structures]]
[[Category: Structural genomic]]
[[Category: Neisseria gonorrhoeae NCCP11945]]
[[Category: Nucleoside diphosphate kinase]]
[[Category: Ssgcid]]
[[Category: Transferase]]

Latest revision as of 13:42, 4 October 2023

Crystal structure of nucleoside diphosphate kinase from Neisseria gonorrhoeae in complex with citrate

5v6d, resolution 1.85Å

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