5v54: Difference between revisions

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'''Unreleased structure'''


The entry 5v54 is ON HOLD
==Crystal structure of 5-HT1B receptor in complex with methiothepin==
<StructureSection load='5v54' size='340' side='right'caption='[[5v54]], [[Resolution|resolution]] 3.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5v54]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Spodoptera_frugiperda Spodoptera frugiperda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V54 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5V54 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=89F:1-methyl-4-[(5~{S})-3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine'>89F</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5v54 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v54 OCA], [https://pdbe.org/5v54 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5v54 RCSB], [https://www.ebi.ac.uk/pdbsum/5v54 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5v54 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/5HT1B_HUMAN 5HT1B_HUMAN] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.


Authors: Yin, W.C., Zhou, X.E., Yang, D., de Waal, P., Wang, M.T., Dai, A., Cai, X., Huang, C.Y., Liu, P., Yin, Y., Liu, B., Caffrey, M., Melcher, K., Xu, Y., Wang, M.W., Xu, H.E., Jiang, Y.
==See Also==
 
*[[5-hydroxytryptamine receptor 3D structures|5-hydroxytryptamine receptor 3D structures]]
Description: Crystal structure of 5-HT1B receptor in complex with methiothepin
__TOC__
[[Category: Unreleased Structures]]
</StructureSection>
[[Category: Zhou, X.E]]
[[Category: Homo sapiens]]
[[Category: Xu, H.E]]
[[Category: Large Structures]]
[[Category: Dai, A]]
[[Category: Spodoptera frugiperda]]
[[Category: Wang, M.T]]
[[Category: Caffrey M]]
[[Category: Melcher, K]]
[[Category: Cai X]]
[[Category: Yang, D]]
[[Category: Dai A]]
[[Category: Yin, Y]]
[[Category: Huang CY]]
[[Category: Jiang, Y]]
[[Category: Jiang Y]]
[[Category: Liu, B]]
[[Category: Liu B]]
[[Category: Liu, P]]
[[Category: Liu P]]
[[Category: Xu, Y]]
[[Category: Melcher K]]
[[Category: Caffrey, M]]
[[Category: Wang MT]]
[[Category: Yin, W.C]]
[[Category: Wang MW]]
[[Category: Huang, C.Y]]
[[Category: Xu HE]]
[[Category: Wang, M.W]]
[[Category: Xu Y]]
[[Category: Cai, X]]
[[Category: Yang D]]
[[Category: De Waal, P]]
[[Category: Yin WC]]
[[Category: Yin Y]]
[[Category: Zhou XE]]
[[Category: De Waal P]]

Latest revision as of 09:29, 23 October 2024

Crystal structure of 5-HT1B receptor in complex with methiothepin

5v54, resolution 3.90Å

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