6bev: Difference between revisions
From Proteopedia
Jump to navigationJump to search
m Protected "6bev" [edit=sysop:move=sysop] |
No edit summary |
||
| (5 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Human Single Domain Sulfurtranferase TSTD1== | |||
<StructureSection load='6bev' size='340' side='right'caption='[[6bev]], [[Resolution|resolution]] 1.04Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6bev]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BEV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BEV FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.043Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6bev FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bev OCA], [https://pdbe.org/6bev PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6bev RCSB], [https://www.ebi.ac.uk/pdbsum/6bev PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6bev ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TSTD1_HUMAN TSTD1_HUMAN] Thiosulfate:glutathione sulfurtransferase (TST) required to produce glutathione persulfide (GSS(-)), a central intermediate in hydrogen sulfide metabolism (PubMed:24981631). Provides the link between the first step in mammalian H(2)S metabolism performed by the sulfide:quinone oxidoreductase (SQOR) which catalyzes the conversion of H(2)S to thiosulfate, and the sulfur dioxygenase (SDO) which uses GSS(-) as substrate (PubMed:24981631). The thermodynamic coupling of the irreversible SDO and reversible TST reactions provides a model for the physiologically relevant reaction with thiosulfate as the sulfane donor (PubMed:24981631).<ref>PMID:24981631</ref> | |||
==See Also== | |||
*[[Sulfurtransferase|Sulfurtransferase]] | |||
== References == | |||
[[Category: | <references/> | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Akey DL]] | |||
[[Category: Banerjee R]] | |||
[[Category: Motl N]] | |||
[[Category: Smith JL]] | |||
Latest revision as of 14:21, 13 March 2024
Human Single Domain Sulfurtranferase TSTD1
| ||||||||||||
