5v54: Difference between revisions
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==Crystal structure of 5-HT1B receptor in complex with methiothepin== | ==Crystal structure of 5-HT1B receptor in complex with methiothepin== | ||
<StructureSection load='5v54' size='340' side='right' caption='[[5v54]], [[Resolution|resolution]] 3.90Å' scene=''> | <StructureSection load='5v54' size='340' side='right'caption='[[5v54]], [[Resolution|resolution]] 3.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5v54]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V54 OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[5v54]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Spodoptera_frugiperda Spodoptera frugiperda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V54 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5V54 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=89F:1-methyl-4-[(5~{S})-3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine'>89F</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.9Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=89F:1-methyl-4-[(5~{S})-3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine'>89F</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5v54 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v54 OCA], [https://pdbe.org/5v54 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5v54 RCSB], [https://www.ebi.ac.uk/pdbsum/5v54 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5v54 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/5HT1B_HUMAN 5HT1B_HUMAN] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. | ||
==See Also== | |||
*[[5-hydroxytryptamine receptor 3D structures|5-hydroxytryptamine receptor 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Caffrey | [[Category: Homo sapiens]] | ||
[[Category: Cai | [[Category: Large Structures]] | ||
[[Category: Dai | [[Category: Spodoptera frugiperda]] | ||
[[Category: Huang | [[Category: Caffrey M]] | ||
[[Category: Jiang | [[Category: Cai X]] | ||
[[Category: Liu | [[Category: Dai A]] | ||
[[Category: Liu | [[Category: Huang CY]] | ||
[[Category: Melcher | [[Category: Jiang Y]] | ||
[[Category: Liu B]] | |||
[[Category: Wang | [[Category: Liu P]] | ||
[[Category: Wang | [[Category: Melcher K]] | ||
[[Category: Xu | [[Category: Wang MT]] | ||
[[Category: Xu | [[Category: Wang MW]] | ||
[[Category: Yang | [[Category: Xu HE]] | ||
[[Category: Yin | [[Category: Xu Y]] | ||
[[Category: Yin | [[Category: Yang D]] | ||
[[Category: Zhou | [[Category: Yin WC]] | ||
[[Category: | [[Category: Yin Y]] | ||
[[Category: Zhou XE]] | |||
[[Category: De Waal P]] | |||
Latest revision as of 09:29, 23 October 2024
Crystal structure of 5-HT1B receptor in complex with methiothepin
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