2f7s: Difference between revisions

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[[Image:2f7s.gif|left|200px]]


{{Structure
==The crystal structure of human Rab27b bound to GDP==
|PDB= 2f7s |SIZE=350|CAPTION= <scene name='initialview01'>2f7s</scene>, resolution 2.70&Aring;
<StructureSection load='2f7s' size='340' side='right'caption='[[2f7s]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=GDP:GUANOSINE-5&#39;-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>
<table><tr><td colspan='2'>[[2f7s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F7S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F7S FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
|GENE= RAB27B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f7s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f7s OCA], [https://pdbe.org/2f7s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f7s RCSB], [https://www.ebi.ac.uk/pdbsum/2f7s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f7s ProSAT]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f7s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f7s OCA], [http://www.ebi.ac.uk/pdbsum/2f7s PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2f7s RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/RB27B_HUMAN RB27B_HUMAN] May be involved in targeting uroplakins to urothelial apical membranes (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f7/2f7s_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f7s ConSurf].
<div style="clear:both"></div>


'''The crystal structure of human Rab27b bound to GDP'''
==See Also==
 
*[[Ras-related protein Rab 3D structures|Ras-related protein Rab 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2F7S is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F7S OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C H.]]
[[Category: Arrowsmith CH]]
[[Category: Bochkarev, A.]]
[[Category: Bochkarev A]]
[[Category: Edwards, A M.]]
[[Category: Edwards AM]]
[[Category: Ismail, S.]]
[[Category: Ismail S]]
[[Category: Park, H W.]]
[[Category: Park HW]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Shen Y]]
[[Category: Shen, Y.]]
[[Category: Sundstrom M]]
[[Category: Sundstrom, M.]]
[[Category: Tempel W]]
[[Category: Tempel, W.]]
[[Category: Wang J]]
[[Category: Wang, J.]]
[[Category: g-protein]]
[[Category: rab]]
[[Category: rab27b]]
[[Category: sgc]]
[[Category: structural genomic]]
[[Category: structural genomics consortium]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:59:02 2008''

Latest revision as of 09:22, 30 August 2023

The crystal structure of human Rab27b bound to GDP

2f7s, resolution 2.70Å

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