6fzt: Difference between revisions
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==Crystal structure of Smad8_9-MH1 bound to the GGCGC site.== | |||
<StructureSection load='6fzt' size='340' side='right'caption='[[6fzt]], [[Resolution|resolution]] 2.46Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6fzt]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FZT OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6FZT FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
[[Category: | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SMAD9, MADH6, MADH9, SMAD8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6fzt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fzt OCA], [http://pdbe.org/6fzt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fzt RCSB], [http://www.ebi.ac.uk/pdbsum/6fzt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fzt ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[[http://www.uniprot.org/uniprot/SMAD9_HUMAN SMAD9_HUMAN]] Heritable pulmonary arterial hypertension. The disease may be caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/SMAD9_HUMAN SMAD9_HUMAN]] Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD9 is a receptor-regulated SMAD (R-SMAD). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Human]] | |||
[[Category: Large Structures]] | |||
[[Category: Kaczmarska, Z]] | [[Category: Kaczmarska, Z]] | ||
[[Category: Marquez, J | [[Category: Macias, M J]] | ||
[[Category: | [[Category: Marquez, J A]] | ||
[[Category: Dna complex]] | |||
[[Category: Smad]] | |||
[[Category: Transcription]] | |||
[[Category: Transcription factor]] | |||
Latest revision as of 06:27, 7 October 2020
Crystal structure of Smad8_9-MH1 bound to the GGCGC site.
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