5xjv: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| (2 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Two intermediate states of conformation switch in dual specificity phosphatase 13a== | ==Two intermediate states of conformation switch in dual specificity phosphatase 13a== | ||
<StructureSection load='5xjv' size='340' side='right' caption='[[5xjv]], [[Resolution|resolution]] 1.69Å' scene=''> | <StructureSection load='5xjv' size='340' side='right'caption='[[5xjv]], [[Resolution|resolution]] 1.69Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5xjv]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XJV OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[5xjv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XJV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XJV FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.69Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xjv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xjv OCA], [https://pdbe.org/5xjv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xjv RCSB], [https://www.ebi.ac.uk/pdbsum/5xjv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xjv ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/DS13A_HUMAN DS13A_HUMAN] Probable protein tyrosine phosphatase. Has a phosphatase activity-independent regulatory role in MAP3K5/ASK1-mediated apoptosis, preventing MAP3K5/ASK1 inhibition by AKT1. Shows no phosphatase activity on MAPK1/ERK2, MAPK8/JNK, MAPK14/p38 and MAP3K5/ASK1.<ref>PMID:20358250</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 18: | Line 19: | ||
</div> | </div> | ||
<div class="pdbe-citations 5xjv" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5xjv" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Dual specificity phosphatase 3D structures|Dual specificity phosphatase 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Chun HJ]] | ||
[[Category: | [[Category: Min HG]] | ||
[[Category: | [[Category: Ryu SE]] | ||
[[Category: | [[Category: Wei CH]] | ||
Latest revision as of 08:04, 22 November 2023
Two intermediate states of conformation switch in dual specificity phosphatase 13a
| ||||||||||||
