6dwe: Difference between revisions
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New page: '''Unreleased structure''' The entry 6dwe is ON HOLD Authors: Chang, C., Michalska, K., Maltseva, N.I., Jedrzejczak, R., McCarren, P., Nag, P.P., Joachimiak, A., Satchell, K., Center fo... |
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The | ==Crystal structure of tryptophan synthase from M. tuberculosis - aminoacrylate- and BRD0059-bound form== | ||
<StructureSection load='6dwe' size='340' side='right'caption='[[6dwe]], [[Resolution|resolution]] 2.69Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6dwe]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6DWE FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.691Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CS:CESIUM+ION'>CS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=HDJ:(2~{R},3~{S},4~{R})-3-[4-[2,6-bis(fluoranyl)-4-methyl-phenyl]phenyl]-4-(fluoranylmethyl)azetidine-2-carbonitrile'>HDJ</scene>, <scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=P1T:2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC+ACID'>P1T</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6dwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dwe OCA], [https://pdbe.org/6dwe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6dwe RCSB], [https://www.ebi.ac.uk/pdbsum/6dwe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6dwe ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TRPA_MYCTU TRPA_MYCTU] The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. | |||
==See Also== | |||
*[[Tryptophan synthase 3D structures|Tryptophan synthase 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mycobacterium tuberculosis H37Rv]] | ||
[[Category: | [[Category: Chang C]] | ||
[[Category: | [[Category: Jedrzejczak R]] | ||
[[Category: | [[Category: Joachimiak A]] | ||
[[Category: | [[Category: Maltseva NI]] | ||
[[Category: | [[Category: McCarren P]] | ||
[[Category: | [[Category: Michalska K]] | ||
[[Category: | [[Category: Nag PP]] | ||
[[Category: Satchell K]] | |||
Latest revision as of 09:56, 25 December 2024
Crystal structure of tryptophan synthase from M. tuberculosis - aminoacrylate- and BRD0059-bound form
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