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'''Unreleased structure'''


The entry 6ee1 is ON HOLD
==Crystal structure of Mycobacterium tuberculosis ICL2 in complex with acetyl-CoA==
 
<StructureSection load='6ee1' size='340' side='right'caption='[[6ee1]], [[Resolution|resolution]] 2.36&Aring;' scene=''>
Authors: Bashiri, G., Bhusal, R., Leung, I.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6ee1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_CDC1551 Mycobacterium tuberculosis CDC1551]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EE1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6EE1 FirstGlance]. <br>
Description: Crystal structure of Mycobacterium tuberculosis ICL2 in complex with acetyl-CoA
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.36&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
[[Category: Bashiri, G]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ee1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ee1 OCA], [https://pdbe.org/6ee1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ee1 RCSB], [https://www.ebi.ac.uk/pdbsum/6ee1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ee1 ProSAT]</span></td></tr>
[[Category: Leung, I]]
</table>
[[Category: Bhusal, R]]
== Function ==
[https://www.uniprot.org/uniprot/ACEA2_MYCTO ACEA2_MYCTO] Involved in the persistence and virulence of M.tuberculosis. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates.<ref>PMID:10572116</ref> <ref>PMID:15895072</ref> <ref>PMID:16879647</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis CDC1551]]
[[Category: Bashiri G]]
[[Category: Bhusal R]]
[[Category: Leung I]]
Retrieved from "https://proteopedia.org/6ee1"