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[[Image:2quq.jpg|left|200px]]


{{Structure
==Crystal Structure of the Essential Inner Kinetochore Protein Cep3p==
|PDB= 2quq |SIZE=350|CAPTION= <scene name='initialview01'>2quq</scene>, resolution 2.800&Aring;
<StructureSection load='2quq' size='340' side='right'caption='[[2quq]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[2quq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QUQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QUQ FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
|GENE= CBF3B, CEP3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2quq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2quq OCA], [https://pdbe.org/2quq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2quq RCSB], [https://www.ebi.ac.uk/pdbsum/2quq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2quq ProSAT]</span></td></tr>
|DOMAIN=
</table>
|RELATEDENTRY=
== Function ==
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2quq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2quq OCA], [http://www.ebi.ac.uk/pdbsum/2quq PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2quq RCSB]</span>
[https://www.uniprot.org/uniprot/CBF3B_YEAST CBF3B_YEAST] Acts as a component of the centromere DNA-binding protein complex CBF3, which is essential for chromosome segregation and movement of centromeres along microtubules. CBF3 is required for the recruitment of other kinetochore complexes to CEN DNA. It plays a role in the attachment of chromosomes to the spindle and binds selectively to a highly conserved DNA sequence called CDEIII, found in centromers and in several promoters.
}}


'''Crystal Structure of the Essential Inner Kinetochore Protein Cep3p'''
==See Also==
 
*[[Centromere protein 3D structure|Centromere protein 3D structure]]
 
__TOC__
==About this Structure==
</StructureSection>
2QUQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QUQ OCA].
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Single protein]]
[[Category: Bellizzi III JJ]]
[[Category: Harrison, S C.]]
[[Category: Harrison SC]]
[[Category: III, J J.Bellizzi.]]
[[Category: cell cycle]]
[[Category: centromere]]
[[Category: chromosomal protein]]
[[Category: dimer]]
[[Category: dna binding protein]]
[[Category: dna-binding]]
[[Category: metal-binding]]
[[Category: nucleus]]
[[Category: phosphorylation]]
[[Category: protein binding]]
[[Category: structural protein]]
[[Category: zinc]]
 
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