6mst: Difference between revisions
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New page: '''Unreleased structure''' The entry 6mst is ON HOLD Authors: Description: Category: Unreleased Structures |
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==Cryo-EM structure of human AA amyloid fibril== | |||
<SX load='6mst' size='340' side='right' viewer='molstar' caption='[[6mst]], [[Resolution|resolution]] 2.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6mst]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MST OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6MST FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.7Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6mst FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mst OCA], [https://pdbe.org/6mst PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6mst RCSB], [https://www.ebi.ac.uk/pdbsum/6mst PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6mst ProSAT]</span></td></tr> | ||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/SAA1_HUMAN SAA1_HUMAN] Secondary amyloidosis. Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA1 protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function. Elevated serum SAA1 protein levels may be associated with lung cancer. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SAA1_HUMAN SAA1_HUMAN] Major acute phase reactant. Apolipoprotein of the HDL complex. | |||
__TOC__ | |||
</SX> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Fandrich M]] | |||
[[Category: Grigorieff N]] | |||
[[Category: Liberta F]] | |||
[[Category: Loerch S]] | |||
[[Category: Rennegarbe M]] | |||
[[Category: Schmidt M]] | |||
Latest revision as of 14:44, 13 March 2024
Cryo-EM structure of human AA amyloid fibril
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