6j6w: Difference between revisions
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New page: '''Unreleased structure''' The entry 6j6w is ON HOLD Authors: Xiao, Z.Y., Cui, L.W., Wang, S., Liu, W. Description: Mutant K23N of heat shock factor 4-DBD [[Category: Unreleased Struct... |
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The entry | ==Mutant K23N of heat shock factor 4-DBD== | ||
<StructureSection load='6j6w' size='340' side='right'caption='[[6j6w]], [[Resolution|resolution]] 1.69Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6j6w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6J6W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6J6W FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.693Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6j6w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6j6w OCA], [https://pdbe.org/6j6w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6j6w RCSB], [https://www.ebi.ac.uk/pdbsum/6j6w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6j6w ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/HSF4_HUMAN HSF4_HUMAN] Early-onset lamellar cataract;Total early-onset cataract. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/HSF4_HUMAN HSF4_HUMAN] DNA-binding protein that specifically binds heat shock promoter elements (HSE). Isoform HSF4A represses transcription while the isoform HSF4B activates transcription.<ref>PMID:16371476</ref> | |||
==See Also== | |||
*[[Heat shock factor|Heat shock factor]] | |||
== References == | |||
[[Category: | <references/> | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Wang | [[Category: Large Structures]] | ||
[[Category: Cui LW]] | |||
[[Category: Liu W]] | |||
[[Category: Wang S]] | |||
[[Category: Xiao ZY]] | |||
Latest revision as of 10:37, 27 March 2024
Mutant K23N of heat shock factor 4-DBD
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