6o7t: Difference between revisions
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==Saccharomyces cerevisiae V-ATPase Vph1-VO== | |||
<SX load='6o7t' size='340' side='right' viewer='molstar' caption='[[6o7t]], [[Resolution|resolution]] 3.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6o7t]] is a 15 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6O7T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6O7T FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6o7t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6o7t OCA], [https://pdbe.org/6o7t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6o7t RCSB], [https://www.ebi.ac.uk/pdbsum/6o7t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6o7t ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/VPP1_YEAST VPP1_YEAST] Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:1491220, PubMed:8798414, PubMed:11278748). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (PubMed:1491220, PubMed:11278748). Is present only in vacuolar V-ATPase complexes; enzymes containing this subunit have a 4-fold higher ratio of proton transport to ATP hydrolysis than complexes containing the Golgi/endosomal isoform and undergo reversible dissociation of V1 and V0 in response to glucose depletion (PubMed:8798414, PubMed:11278748).<ref>PMID:11278748</ref> <ref>PMID:1491220</ref> <ref>PMID:8798414</ref> | |||
==See Also== | |||
*[[ATPase 3D structures|ATPase 3D structures]] | |||
== References == | |||
[[Category: | <references/> | ||
__TOC__ | |||
</SX> | |||
[[Category: Large Structures]] | |||
[[Category: Saccharomyces cerevisiae]] | |||
[[Category: Beilsten-Edmands V]] | |||
[[Category: Bueler SA]] | |||
[[Category: Robinson CV]] | |||
[[Category: Rubinstein JL]] | |||
[[Category: Vasanthakumar T]] | |||
[[Category: Wu D]] | |||
Latest revision as of 09:23, 20 March 2024
Saccharomyces cerevisiae V-ATPase Vph1-VO
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