Growth differentiation factor: Difference between revisions

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*'''GDF-11''' or '''bone morphogenetic protein 11''' is a circulating factor that reverses age-related cardiac hypertrophy<ref>PMID:23663781</ref>.
*'''GDF-11''' or '''bone morphogenetic protein 11''' is a circulating factor that reverses age-related cardiac hypertrophy<ref>PMID:23663781</ref>.
*'''GDF-15''' or '''placental bone morphogenetic protein''' protects the hart from ischmia and reperfusion injury<ref>PMID:16484622</ref>.
*'''GDF-15''' or '''placental bone morphogenetic protein''' protects the hart from ischmia and reperfusion injury<ref>PMID:16484622</ref>.
</StructureSection>
See also [[Growth factors]] and [[Bone morphogenetic protein]].
 
==3D structures of growth differentiation factor==
==3D structures of growth differentiation factor==
[[Growth differentiation factor 3D STRUCTURES]]


Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
</StructureSection>
{{#tree:id=OrganizedByTopic|openlevels=0|
 
*GDF-2
 
**[[1zkz]], [[4mpl]], [[5i05]] – hGDF residues 320-493 – human  <br />
**[[4fao]] – hGDF residues 320-493 + serine/threonine-protein kinase receptor + activin receptor<br />
**[[5hzw]] – hGDF residues 320-493 + MBP/endoglin  <br />
**[[4ycg]], [[4yci]] – mGDF residues 23-318 + hGDF residues 320-493 - mouse<br />
 
*GDF-5
 
**[[2bhk]], [[1waq]] – hGDF  <br />
**[[3evs]] – hGDF + bone morphogenetic receptor  <br />
**[[3qb4]] – hGDF (mutant) + bone morphogenetic receptor  <br />
**[[5hk5]] – hGDF + gremlin-2  <br />
 
*GDF-8
 
**[[5ji1]] – mGDF – mouse  <br />
**[[3hh2]] – mGDF + follistatin  <br />
**[[3sek]] – mGDF + follistatin-related protein  <br />
**[[5nsx]], [[5ntu]] – hGDF (mutant)  <br />
**[[5f3h]], [[5f3b]] – hGDF + antibody  <br />
 
*GDF-11
 
**[[5uhm]], [[5e4g]] – hGDF  <br />
**[[5jhw]] – hGDF + follistatin  <br />
 
*GDF-15


**[[5vz3]], [[5vt2]] – hGDF  <br />
**[[5vz4]] – hGDF + GDNF family receptor a-like  <br />
}}
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Latest revision as of 13:45, 1 August 2021

Structure of growth differentiation factor GDF-5 (green and aqua) complex with bone morphogenetic receptor (pink and olive) (PDB entry 3evs)

Drag the structure with the mouse to rotate

References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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