Glycosyltransferase 3D structures: Difference between revisions

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New page: ==3D structures of glycosyltransferase== Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *Cyclodextrin GT (CGT) **...
 
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|
*Cyclodextrin GT (CGT)
*Cyclodextrin GT (CGT)
**[[1cxi]], [[1cdg]], [[1cgt]], [[1cgu]] - BcCGT  – ''Bacillus circulans''
**[[1cxi]], [[1cdg]], [[1cgt]], [[1cgu]] - BcCGT  – ''Bacillus circulans''
**[[1tcm]], [[4cgt]], [[7cgt]], [[1kck]], [[1kcl]], [[1ot1]], [[1ot2]], [[1pez]], [[1pj9]], [[1v3j]], [[1v3k]], [[1cgv]], [[1cgw]] - BcCGT  (mutant)
**[[1tcm]], [[4cgt]], [[7cgt]], [[1kck]], [[1kcl]], [[1ot1]], [[1ot2]], [[1pez]], [[1pj9]], [[1v3j]], [[1v3k]], [[1cgv]], [[1cgw]] - BcCGT  (mutant)
**[[1ciu]] – TtCGT – ''Thermoanaerobacterium thermosulfurigenes''
**[[1ciu]] – TtCGT – ''Thermoanaerobacterium thermosulfurigenes''
**[[3bmv]], [[3bmw]] – TtCGT (mutant)<br />
**[[3bmv]], [[3bmw]] – TtCGT (mutant)<br />
**[[1cyg]] – CGT – ''Geobacillus stearothermophilus''<br />
**[[1cyg]] – CGT – ''Geobacillus stearothermophilus''<br />
Line 17: Line 12:
**[[1pam]] - BaCGT<br />
**[[1pam]] - BaCGT<br />
**[[4jcl]] - PmCGT – ''Paenibacillus macerans''<br />
**[[4jcl]] - PmCGT – ''Paenibacillus macerans''<br />
**[[6aij]] - PmCGT (mutant) <br />
**[[3wms]], , [[7lvy]], [[7mco]] [[6aij]] - PmCGT (mutant) <br />
 
*''CGT binary complexes''
*''CGT binary complexes''
**[[1cxe]], [[1cxh]] – BcCGT  + substrate  
**[[1cxe]], [[1cxh]] – BcCGT  + substrate  
**[[1cxf]], [[5cgt]], [[8cgt]], [[9cgt]], [[1cxk]], [[1eo5]], [[1eo7]] - BcCGT  (mutant) + substrate
**[[1cxf]], [[5cgt]], [[8cgt]], [[9cgt]], [[1cxk]], [[1eo5]], [[1eo7]] - BcCGT  (mutant) + substrate
**[[3cgt]] - BcCGT  (mutant) + β-cyclodextrin
**[[3cgt]] - BcCGT  (mutant) + β-cyclodextrin
**[[1d3c]] - BcCGT  (mutant) + γ-cyclodextrin
**[[1d3c]] - BcCGT  (mutant) + γ-cyclodextrin
**[[6cgt]] - BcCGT  (mutant) + HOXA
**[[6cgt]] - BcCGT  (mutant) + HOXA
**[[2dij]], [[1dtu]] - BcCGT  (mutant) + inhibitor
**[[2dij]], [[1dtu]] - BcCGT  (mutant) + inhibitor
**[[1cxl]] - BcCGT  (mutant) + reaction intermediate
**[[1cxl]] - BcCGT  (mutant) + reaction intermediate
**[[2cxg]], [[1ukq]] – BcCGT + acarbose-derivative
**[[2cxg]], [[1ukq]] – BcCGT + acarbose-derivative
**[[1uks]], [[1ukt]], [[1v3l]], [[1v3m]] – BcCGT (mutant)  + acarbose-derivative<br />
**[[1uks]], [[1ukt]], [[1v3l]], [[1v3m]] – BcCGT (mutant)  + acarbose-derivative<br />
**[[1ded]] - BaCGT (mutant)  + acarbose<br />
**[[1ded]] - BaCGT (mutant)  + acarbose<br />
**[[1i75]] – BaCGT + deoxyjirimycin<br />
**[[1i75]] – BaCGT + deoxyjirimycin<br />
**[[1a47]] – TtCGT + inhibitor
**[[1a47]] – TtCGT + inhibitor
*Maltose GT
*Maltose GT
**[[1gju]], [[1lwh]] – TmMCG – ''Thermotoga maritima''
**[[1gju]], [[1lwh]] – TmMCG – ''Thermotoga maritima''
**[[1gjw]] – TmMCG + maltose
**[[1gjw]] – TmMCG + maltose
**[[1lwj]] - TmMGT + acarbose
**[[1lwj]] - TmMGT + acarbose
*Human GT
*Human GT
**[[1lz0]] – hGT A - hGT A catalytic domain + inhibitor
**[[1lz0]] – hGT A - hGT A catalytic domain + inhibitor
**[[1r7y]], [[1r81]] - hGT A catalytic domain + inhibitor + UDP-derivative
**[[1r7y]], [[1r81]] - hGT A catalytic domain + inhibitor + UDP-derivative
**[[1lz7]] – hGT B catalytic domain
**[[1lz7]] – hGT B catalytic domain
**[[1r7u]], [[1r7x]] - hGT B catalytic domain + inhibitor
**[[1r7u]], [[1r7x]] - hGT B catalytic domain + inhibitor
**[[1r80]], [[1r82]] - hGT B catalytic domain + inhibitor + UDP-derivative
**[[1r80]], [[1r82]] - hGT B catalytic domain + inhibitor + UDP-derivative
**[[1lzi]] – hGT A catalytic domain + UDP + H antigen acceptor
**[[1lzi]] – hGT A catalytic domain + UDP + H antigen acceptor
**[[1lzj]] – hGT B catalytic domain + UDP + H antigen acceptor
**[[1lzj]] – hGT B catalytic domain + UDP + H antigen acceptor
**[[1r7t]], [[1r7v]] - hGT ABO(H) + inhibitor
**[[1r7t]], [[1r7v]] - hGT ABO(H) + inhibitor
**[[1wt0]], [[1wsz]], [[1wt3]], [[2o1f]], [[2o1g]], [[3i0c]], [[3i0h]], [[1xz6]], [[2i7b]] – hGT ABO(H) (mutant)
**[[1wt0]], [[1wsz]], [[1wt3]], [[2o1f]], [[2o1g]], [[3i0c]], [[3i0h]], [[1xz6]], [[2i7b]] – hGT ABO(H) (mutant)
**[[1wt1]], [[1wt2]], [[2o1h]], [[3i0d]], [[3i0i]], [[2y7a]] - hGT ABO(H) (mutant) + UDP
**[[1wt1]], [[1wt2]], [[2o1h]], [[3i0d]], [[3i0i]], [[2y7a]] - hGT ABO(H) (mutant) + UDP
**[[3i0e]], [[3i0j]] - hGT ABO(H) (mutant) + H-antigen
**[[3i0e]], [[3i0j]] - hGT ABO(H) (mutant) + H-antigen
**[[3i0f]], [[3i0k]] - hGT ABO(H) (mutant) + H-antigen + UDP
**[[3i0f]], [[3i0k]] - hGT ABO(H) (mutant) + H-antigen + UDP
**[[3i0g]], [[3i0l]] - hGT ABO(H) (mutant) + DA + UDP-Gal
**[[3i0g]], [[3i0l]] - hGT ABO(H) (mutant) + DA + UDP-Gal
*Oleandomycin GT
*Oleandomycin GT
**[[2iya]], [[2iyf]], [[4m60]], [[4m7p]] – SaGT – ''Strepromyces antibioticus''<br />
**[[2iya]], [[2iyf]], [[4m60]], [[4m7p]] – SaGT – ''Strepromyces antibioticus''<br />
**[[4m83]] – SaGT + UDP + erythromycin<br />
**[[4m83]] – SaGT + UDP + erythromycin<br />
*Hydroquinone GT
*Hydroquinone GT
**[[2vce]] – AtGT – ''Arabidopsis thaliana''<br />
**[[2vce]] – AtGT – ''Arabidopsis thaliana''<br />
**[[2vch]], [[2vg8]] – AtGT + UDP
**[[2vch]], [[2vg8]] – AtGT + UDP
*UDP GT
*UDP GT
 
**[[6pnt]], [[7lvy]], [[7mco]] – GT – spider mite <br />
**[[5tme]], [[5tmb]] – rGT OS 79 + UDP - rice <br />
**[[7ery]] – GT - rice<br />
**[[5tme]], [[5tmb]] – rGT OS 79 + UDP <br />
**[[6bk0]], [[6bk1]], [[6bk2]] - rGT OS 79 (mutant) + UDP <br />
**[[6bk0]], [[6bk1]], [[6bk2]] - rGT OS 79 (mutant) + UDP <br />
**[[5tmd]], [[6bk3]] – rGT OS 79 + UDP derivative + trichothecene<br />
**[[5tmd]], [[6bk3]] – rGT OS 79 + UDP derivative + trichothecene<br />
**[[7erx]], [[7es0]], [[7es1]], [[7es2]] – rGT + UDP + sweetener<br />
**[[6ij9]] – AtGT + UDP <br />
**[[6ijd]] – AtGT + quercetin <br />
**[[6ija]] – AtGT + UDP + rhamnose <br />
**[[5v2j]], [[5v2k]], [[5u6s]] – AtGT + UDP + laminaribiose + Br-benzoate<br />
**[[5u6n]], [[5u6m]] – AtGT + UDP + laminaribiose + salicilate<br />
**[[6lf6]], [[7q3s]] – GT + UDP - maize<br />
**[[7va8]], [[7vaa]] – GT + UDP - mango<br />
**[[7cyw]] – bwGT + UTP - buckwheat<br />
**[[6llz]] – bwGT + UDP-glucose<br />
**[[7vej]] – pwGT + UDP derivative + antioxidant - pokeweed<br />
**[[7vek]] – pwGT + UDP derivative + capsaicin<br />
**[[7vel]] – pwGT + UDP derivative <br />
**[[5xvm]] - yGT 51 – yeast<br />
**[[5xvm]] - yGT 51 – yeast<br />
**[[7yuy]] - yGT (mutant) <br />
**[[5gl5]] - yGT 51 + UDP-glucose <br />
**[[5gl5]] - yGT 51 + UDP-glucose <br />
**[[5v2j]], [[5v2k]], [[5u6s]] – AtGT + UDP + laminaribiose + Br-benzoate<br />
**[[5gl5]] - yGT 51 + UDP-glucose <br />
**[[5u6n]], [[5u6m]] – AtGT + UDP + laminaribiose + salicilate<br />
**[[6o86]], [[6o87]], [[6inf]], [[6kvi]] – SrGT + UDP – ''Stevia rebaudiana''<br />
**[[6o86]], [[6o87]] – SrGT + UDP – ''Stevia rebaudiana''<br />
**[[6ing]] – SrGT (mutant) + UDP <br />
**[[6o88]] – SrGT + UDP + revaudioside<br />
**[[6kvj]] – SrGT + UDP derivative<br />
 
**[[6o88]], [[6inh]], [[6ini]], [[6kvk]], [[6kvl]] – SrGT + UDP + substrate<br />
**[[6su6]] - PtGT + UDP-glucose – ''Persicaria tinctoria''<br />
**[[6su7]] - PtGT + dichloroaniline<br />
**[[7vlb]], [[7vm0]] – GT + UDP – ''Bacillus subtilis''<br />
*C-GT
*C-GT
 
**[[6jtd]] – GT + UDP – ''Trollius chinensis''<br />
**[[6jtd]] – GT + UDP – Trollius chinensis<br />
**[[6l7h]] – GgGT + UDP + nothofagin – ''Glycyrrhiza glabra''<br />
 
**[[6l5p]], [[6l5r]] - GgGT + UDP-glucose <br />
**[[6l5q]] - GgGT + UDP-galactose <br />
**[[7c2x]] – GT + UDP + glycyrrhetinic acid derivative – ''Glycyrrhiza uralensis''<br />
*Flavonoid GT
*Flavonoid GT
**[[3hbf]] – MtGT + UDP + myricetin – ''Medicago truncatula''
**[[3hbf]] – MtGT + UDP + myricetin – ''Medicago truncatula''
**[[3hbj]] - MtGT + UDP
**[[3hbj]] - MtGT + UDP
**[[2pq6]] - MtGT
**[[2pq6]] - MtGT
**[[2c1x]], [[2c1z]] – GT + UDP – ''Vitis vinifera''
**[[2c1x]], [[2c1z]] – GT + UDP – ''Vitis vinifera''
*Peptidoglycan GT
*Peptidoglycan GT
**[[4jbf]], [[4ovd]] – ApGT – ''Atopobium parvulum''<br />
**[[4jbf]], [[4ovd]] – ApGT – ''Atopobium parvulum''<br />
**[[4mnr]] – GT D,D transpeptidase domain – ''Eggerthella lenta''<br />
**[[4mnr]] – GT D,D transpeptidase domain – ''Eggerthella lenta''<br />
Line 123: Line 99:
**[[6bar]] – TtGT RODA – ''Thermus thermophilus''<br />
**[[6bar]] – TtGT RODA – ''Thermus thermophilus''<br />
**[[6bas]] – TtGT RODA (mutant) <br />
**[[6bas]] – TtGT RODA (mutant) <br />
**[[6pl5]], [[6pl6]] – TtGT RODA + Fts1 + peptide <br />
**[[3hzs]], [[3vmq]], [[5zzk]] – SaGT - ''Staphylococcus aureus''<br />
**[[3hzs]], [[3vmq]], [[5zzk]] – SaGT - ''Staphylococcus aureus''<br />
**[[6ftb]] – SaGT + moenomycin <br />
**[[6ftb]] – SaGT + moenomycin <br />
 
**[[3nb6]], [[3nb7]] – AaGT + moenomycin – ''Aquifex aeolicus''<br />
*Pseudo-GT VldE
**[[3vdm]] – ShyVldE – ''Streptococcus hygroscopicus''<br />
**[[3vdn]], [[4f96]] – ShyVldE + GDP<br />
**[[4f9f]] – ShyVldE + GDP + trehalose<br />
**[[4f97]] – ShyVldE + GDP + fungicide<br />
*Various GT
*Various GT
 
**[[3otk]] – GT catalytic domain - mouse<br />
**[[5a01]] – DmO-GT catalytic domain (mutant) – ''Drosophila melanogaster''<br />
**[[6jel]], [[6lzx]], [[6lzy]] – apGT – american pokeweed <br />
**[[6l90]] – mfGT – monk’s fruit<br />
**[[6l8w]], [[6l8x]] – mfGT (mutant) <br />
**[[7w09]], [[7w0k]], [[7w0z]], [[7w10]], [[7w11]], [[7w1b]], [[7w1h]] – GT – mudar<br />
**[[2iuy]], [[2iv3]] – SvGT – ''Stretptomyces  viridochromogenes''
**[[2iuy]], [[2iv3]] – SvGT – ''Stretptomyces  viridochromogenes''
**[[2jjm]] - BaGT – ''Bacillus anthracis''<br />
**[[2jjm]] - BaGT – ''Bacillus anthracis''<br />
**[[3oy2]] – PcvGT – ''Paramecium chiorela virus''<br />
**[[3oy2]] – PcvGT – ''Paramecium chiorela virus''<br />
**[[3pnn]] – GT – ''Porphyromonas gingivalis''
**[[3pnn]] – GT – ''Porphyromonas gingivalis''
**[[2q3e]], [[3q3i]], [[3q3e]] – ApGT – ''Actinobacillus pleuropneumomiae''
**[[2q3e]], [[3q3i]], [[3q3e]] – ApGT – ''Actinobacillus pleuropneumomiae''
**[[1iir]] – AoUDP-GT – ''Amycolatopsis orientalis''
**[[1iir]] – AoUDP-GT – ''Amycolatopsis orientalis''
**[[3h4i]], [[3h4t]] – GT chimera
**[[3h4i]], [[3h4t]] – GT chimera
**[[1cwy]] – GT – ''Thermus aquaticus''
**[[1cwy]] – GT – ''Thermus aquaticus''
**[[2iv7]], [[2iw1]], [[4rap]] – EcGT  - ''Escherichia coli''<br />
**[[2iv7]], [[2iw1]], [[4rap]] – EcGT  - ''Escherichia coli''<br />
**[[4xyw]] – EcGT (mutant) <br />
**[[4xyw]] – EcGT (mutant) <br />
**[[2xci]] – AaGT – ''Aquifex aeolicus''
**[[2xci]] – AaGT – ''Aquifex aeolicus''
**[[3ia7]] – MeGT Calg4 – ''Micromonospora echinospora''
**[[3ia7]] – MeGT Calg4 – ''Micromonospora echinospora''
**[[3otk]] – GT catalytic domain - mouse<br />
**[[4ayl]] - BoGT – ''Bacterioides ovatus''<br />
**[[4ayl]] - BoGT – ''Bacterioides ovatus''<br />
**[[4an4]], [[4amb]], [[4amg]] – GT Snogd – ''Streptomyces nogalater''<br />
**[[4an4]], [[4amb]], [[4amg]] – GT Snogd – ''Streptomyces nogalater''<br />
**[[3wad]] – ShGT – ''Streptomyces halstedii''<br />
**[[3wad]] – ShGT – ''Streptomyces halstedii''<br />
**[[4pqg]] – GT- ''Streptococcus pneumoniae''<br />
**[[4pqg]] – GT- ''Streptococcus pneumoniae''<br />
**[[4wq6]] – GT- ''Streptococcus agalactiae''<br />
**[[5du2]] - GT – ''Actinomadura verrucosospora''<br />
**[[5du2]] - GT – ''Actinomadura verrucosospora''<br />
**[[5a01]] – DmO-GT catalytic domain (mutant) – ''Drosophila melanogaster''<br />
**[[6p61]] – GT – ''Leptospira borgpetersenii''<br />
**[[6p61]] – GT – ''Leptospira borgpetersenii''<br />
 
**[[7mi0]] – GT – ''Ricketsia africae''<br />
**[[6j32]] – KiGT – ''Kitasatospora''<br />
**[[7yp4]] – StrGT – ''Streptomyces''<br />
*Various GT complexes
*Various GT complexes
 
**[[6jem]] – apGT + UDP-glucose + resveratrol<br />
**[[6jen]] – apGT + UDP-glucose + pterostilbene<br />
**[[6l8z]] – mfGT (mutant) + UDP-glucose <br />
**[[1nzd]] – T4β-GT + UDP-glucose – Phage T4
**[[1nzd]] – T4β-GT + UDP-glucose – Phage T4
**[[2nzf]], [[1nzf]] - T4β-GT (mutant) + UDP-glucose<br />
**[[2nzf]], [[1nzf]] - T4β-GT (mutant) + UDP-glucose<br />
**[[3vmr]], [[3vms]], [[3vmt]] – SaGT + lipid II analog<br />
**[[3vmr]], [[3vms]], [[3vmt]] – SaGT + lipid II analog<br />
**[[3mbo]] – BaGT + UDP + malate <br />
**[[3mbo]] – BaGT + UDP + malate <br />
**[[3oy7]] – PcvGT + GDP-mannose <br />
**[[3oy7]] – PcvGT + GDP-mannose <br />
**[[6llw]] – ApGT + UDP<br />
**[[3q3h]] – ApGT + UDP-Glc<br />
**[[3q3h]] – ApGT + UDP-Glc<br />
**[[6lzz]] – ApGT + UDP-glucose <br />
**[[6llg]] – ApGT + benzamidine<br />
**[[1pn3]], [[1pnv]], [[1rrv]] – AoGT + TDP + vancomycin<br />
**[[1pn3]], [[1pnv]], [[1rrv]] – AoGT + TDP + vancomycin<br />
**[[4rb4]] – EcGT (mutant) + ADP-heptose<br />
**[[4rb4]] – EcGT (mutant) + ADP-heptose<br />
Line 172: Line 155:
**[[2xcu]] – AaGT + CMP<br />
**[[2xcu]] – AaGT + CMP<br />
**[[3iaa]] – MeGT Calg2 + TDP
**[[3iaa]] – MeGT Calg2 + TDP
**[[3rsc]] - MeGT Calg2 + TDP + calicheamicin<br />
**[[3rsc]] - MeGT Calg2 + TDP + calicheamicin<br />
**[[4ayj]] – BoGT + glucose + galactose + fucose <br />
**[[4ayj]] – BoGT + glucose + galactose + fucose <br />
Line 186: Line 168:
**[[6ejk]] - CjGT + nerylneryl pyrophosphate + UDP-galactosamine  <br />
**[[6ejk]] - CjGT + nerylneryl pyrophosphate + UDP-galactosamine  <br />
**[[5v4a]] - GT + UDP – ''Streptococcus sanguinis''<br />
**[[5v4a]] - GT + UDP – ''Streptococcus sanguinis''<br />
 
**[[6d9t]] – SaGT + UDP<br />
**[[6n1x]] - SaGT + UDP + acetylglucosamine  <br />
**[[6j31]] – KiGT + polypeptide<br />
**[[7yp3]] – StrGT + drug <br />
*β-1,4-galactosyltransferase 1 (BGT)
*β-1,4-galactosyltransferase 1 (BGT)
**[[6fwu]], [[6fwt]] - hBGT 1 catalytic domain<br />
**[[6fwu]], [[6fwt]] - hBGT 1 catalytic domain<br />
**[[2fy7]] - hBGT 1 catalytic domain (mutant) <br />
**[[2fy7]] - hBGT 1 catalytic domain (mutant) <br />
Line 194: Line 178:
**[[1pzt]], [[4krv]] - bBGT 1 catalytic domain (mutant) <br />
**[[1pzt]], [[4krv]] - bBGT 1 catalytic domain (mutant) <br />
**[[3lw6]] - DmBGT 7 catalytic domain (mutant)  
**[[3lw6]] - DmBGT 7 catalytic domain (mutant)  
*''BGT 1 binary complexes''
*''BGT 1 binary complexes''
**[[1oqm]] - bBGT catalytic domain + UDP-N-acetylgalactosamine<br />
**[[1oqm]] - bBGT catalytic domain + UDP-N-acetylgalactosamine<br />
**[[2fya]] - hBGT 1 catalytic domain (mutant) + Mn<br />
**[[2fya]] - hBGT 1 catalytic domain (mutant) + Mn<br />
Line 202: Line 184:
**[[1fr8]], [[1o0r]] - bBGT 1 catalytic domain + UDP-galactose<br />
**[[1fr8]], [[1o0r]] - bBGT 1 catalytic domain + UDP-galactose<br />
**[[1tw5]] - bBGT catalytic domain (mutant) + chitobiose<br />
**[[1tw5]] - bBGT catalytic domain (mutant) + chitobiose<br />
**[[1nf5]] - bBGT + α-lactalbumin<br />
**[[4l41]] - bBGT 1 (mutant) + α-lactalbumin<br />
**[[1o23]] - bBGT catalytic domain + UDP-glucose<br />
**[[1o23]] - bBGT catalytic domain + UDP-glucose<br />
**[[1oqm]] - bBGT catalytic domain + UDP-N-acetylgalactosamine<br />
**[[1oqm]] - bBGT catalytic domain + UDP-N-acetylgalactosamine<br />
*''BGT 1 ternary complexes''
*''BGT 1 ternary complexes''
**[[2fyb]] - hBGT 1 catalytic domain (mutant) + Mn + UDP<br />
**[[2fyb]] - hBGT 1 catalytic domain (mutant) + Mn + UDP<br />
**[[2ae7]]-  hBGT 1 catalytic domain + UDP + pentasaccharide<br />
**[[2ae7]]-  hBGT 1 catalytic domain + UDP + pentasaccharide<br />
**[[2aec]], [[2aes]], [[2agd]] - hBGT 1 catalytic domain + UDP + GlcNAc + mannose<br />
**[[2aec]], [[2aes]], [[2agd]] - hBGT 1 catalytic domain + UDP + GlcNAc + mannose<br />
**[[2fyc]] - hBGT 1 catalytic domain (mutant) + UDP-galactose + Ca + α-lactalbumin<br />
**[[3ee5]] - hBGT 1 catalytic domain (mutant) + UDP + GlcNAc-β1,3-gal-β-naphthalenemethanol<br />
**[[3ee5]] - hBGT 1 catalytic domain (mutant) + UDP + GlcNAc-β1,3-gal-β-naphthalenemethanol<br />
**[[2fyd]] - hBGT 1 catalytic domain + UDP-GlcNAc + Mn + α-lactalbumin<br /> (mutant) + glucose<br />
**[[2ah9]] - hBGT 1 catalytic domain + UDP + chitotriose<br />
**[[2ah9]] - hBGT 1 catalytic domain + UDP + chitotriose<br />
**[[1nhe]], [[1nkh]] - bBGT 1 catalytic domain + UDP + α-lactalbumin<br />
*Beta-1,4-galactosyltransferase complex with alpha-lactalbumin or lactose synthase
**[[1yro]] - bBGT 1 catalytic domain (mutant) + UDP-galactose + α-lactalbumin<br />
**[[4l41]] - hBGT 1 (mutant) + α-lactalbumin<br />
**[[1nwg]] - bBGT catalytic domain + N-butanoyl-glucoamine + α-lactalbumin<br />
**[[1nf5]] - mBGT + b/α-lactalbumin<br />
**[[1nmm]], [[1nqi]], [[1pzy]], [[1o7q]] - bBGT 1 catalytic domain + UDP + GlcNAc<br />
**[[2fyc]] - mBGT 1 catalytic domain (mutant) + UDP-galactose + Ca + b/alpha-lactalbumin<br />
 
**[[2fyd]] - mBGT 1 catalytic domain + UDP-GlcNAc + Mn + b/alpha-lactalbumin<br />
**[[1nhe]], [[1nkh]] - mBGT 1 catalytic domain + UDP + b/alpha-lactalbumin<br />
**[[1yro]] - mBGT 1 catalytic domain (mutant) + UDP-galactose + b/alpha-lactalbumin<br />
**[[1nwg]] - mBGT catalytic domain + N-butanoyl-glucoamine + b/alpha-lactalbumin<br />
**[[1nmm]], [[1nqi]], [[1pzy]], [[1o7q]] - mBGT 1 catalytic domain + b/α-lactalbumin + UDP + GlcNAc<br />
**[[1o23]] - mBGT catalytic domain + b/α-lactalbumin + UDP-glucose<br />
**[[1oqm]] - mBGT catalytic domain + b/α-lactalbumin + UDP-N-acetylgalactosamine<br />
*β-1,4-galactosyltransferase 7 (BGT)
*β-1,4-galactosyltransferase 7 (BGT)
**[[1tvy]], [[1tw1]], [[4lw3]] - bBGT 7 catalytic domain (mutant) + UDP-galactose<br />
**[[1tvy]], [[1tw1]], [[4lw3]] - bBGT 7 catalytic domain (mutant) + UDP-galactose<br />
**[[4irq]], [[4irp]] - bBGT 7 catalytic domain + UDP<br />
**[[4irq]], [[4irp]] - bBGT 7 catalytic domain + UDP<br />
Line 228: Line 209:
**[[4m4k]] - bBGT 7 catalytic domain (mutant) + UDP-galactose + xylobiose<br />
**[[4m4k]] - bBGT 7 catalytic domain (mutant) + UDP-galactose + xylobiose<br />
**[[3lw6]] - DmBGT 7 catalytic domain (mutant)<br />
**[[3lw6]] - DmBGT 7 catalytic domain (mutant)<br />
*α-1,3-galactosyltransferase (AGT)
*α-1,3-galactosyltransferase (AGT)
**[[1vzu]], [[1vzx]], [[2i7b]] - hAGT catalytic domain (mutant)<br />
**[[1vzu]], [[1vzx]], [[2i7b]] - hAGT catalytic domain (mutant)<br />
**[[2i7b]] - hAGT catalytic domain (mutant)<br />
**[[2i7b]] - hAGT catalytic domain (mutant)<br />
**[[1g8o]], [[1fg5]], [[2jco]] - bAGT catalytic domain<br />
**[[1g8o]], [[1fg5]], [[2jco]] - bAGT catalytic domain<br />
**[[2jcl]] – bAGT catalytic domain (mutant) <br />
**[[2jcl]] – bAGT catalytic domain (mutant) <br />
*''AGT binary complexes''
*''AGT binary complexes''
**[[1ziz]], [[1zjp]] - hAGT catalytic domain + galactose<br />
**[[1ziz]], [[1zjp]] - hAGT catalytic domain + galactose<br />
**[[1zj0]] - hAGT catalytic domain + lactose<br />
**[[1zj0]] - hAGT catalytic domain + lactose<br />
Line 250: Line 227:
**[[2vs4]], [[2vs5]], [[2vxl]], [[2vxm]], [[2vs3]] - bAGT catalytic domain (mutant) + UDP-galactose<br />
**[[2vs4]], [[2vs5]], [[2vxl]], [[2vxm]], [[2vs3]] - bAGT catalytic domain (mutant) + UDP-galactose<br />
**[[2vs3]] - bAGT catalytic domain  + UDP-galactose<br />
**[[2vs3]] - bAGT catalytic domain  + UDP-galactose<br />
*''AGT ternary complexes''
*''AGT ternary complexes''
**[[1r7u]], [[1r7x]] - hAGT catalytic domain + inhibitor + fucose<br />
**[[1r7u]], [[1r7x]] - hAGT catalytic domain + inhibitor + fucose<br />
**[[1r80]] - hAGT catalytic domain + UDP + inhibitor + fucose<br />
**[[1r80]] - hAGT catalytic domain + UDP + inhibitor + fucose<br />
Line 262: Line 237:
**[[1gx4]] - bAGT catalytic domain + UDP + N-acetyl lactosamine<br />
**[[1gx4]] - bAGT catalytic domain + UDP + N-acetyl lactosamine<br />
**[[1gww]] - bAGT catalytic domain + UDP + glucose<br />
**[[1gww]] - bAGT catalytic domain + UDP + glucose<br />
*Fucosylglycoprotein 3-AGT (GTB) or histo-blood group ABO system transferase
*Fucosylglycoprotein 3-AGT (GTB) or histo-blood group ABO system transferase
**[[2rit]], [[4kxo]] – hGTB<br />
**[[2rit]], [[4kxo]] – hGTB<br />
**[[2pgv]], [[2pgy]], [[2riz]], [[2rj5]], [[1wsz]], [[2o1f]], [[2o1g]], [[5cql]], [[5cqm]], [[5cqn]], [[5cqo]], [[5cqp]], [[5cmf]], [[5cmg]], [[5cmh]], [[5cmi]], [[5cmj]], [[3ioh]], [[6bjm]], [[6bjl]], [[6bjk]], [[6bjj]], [[6bji]], [[6gwz]], [[6gwy]], [[6gx2]], [[6gx1]], [[6gx0]] – hGTB (mutant) <br />
**[[2pgv]], [[2pgy]], [[2riz]], [[2rj5]], [[1wsz]], [[2o1f]], [[2o1g]], [[5cql]], [[5cqm]], [[5cqn]], [[5cqo]], [[5cqp]], [[5cmf]], [[5cmg]], [[5cmh]], [[5cmi]], [[5cmj]], [[3ioh]], [[6bjm]], [[6bjl]], [[6bjk]], [[6bjj]], [[6bji]], [[6gwz]], [[6gwy]], [[6gx2]], [[6gx1]], [[6gx0]] – hGTB (mutant) <br />
Line 273: Line 246:
**[[5m79]], [[5m7a]] – hGTB (mutant) + UMP<br />
**[[5m79]], [[5m7a]] – hGTB (mutant) + UMP<br />
**[[4y62]], [[4y63]], [[4y64]] - hGTB + amino acid analog<br />
**[[4y62]], [[4y63]], [[4y64]] - hGTB + amino acid analog<br />
**[[3u0x]] – hGTB + inhibitor<br />
**[[3u0x]], [[4kc1]], [[4kc2]], [[4kc4]] – hGTB + inhibitor<br />
**[[3u0y]] – hGTB (mutant) + UDP + inhibitor<br />
**[[3u0y]] – hGTB (mutant) + UDP + inhibitor<br />
**[[2riy]] – hGTB + H-antigen acceptor<br />
**[[2riy]] – hGTB + H-antigen acceptor<br />
Line 292: Line 265:
**[[1zi1]] - hGTB catalytic domain + lactose<br />
**[[1zi1]] - hGTB catalytic domain + lactose<br />
**[[1zi3]] - hGTB catalytic domain + acetylactosamine
**[[1zi3]] - hGTB catalytic domain + acetylactosamine
*Dolicyl-diphosphooligosaccharide—protein GT or oligosaccharyl transferase or Ost6p
**[[6s7o]], [[6s7t]] – hGT – Cryo EM<br />
**[[8b6l]] – hGT subunit STT3A in translocon complex– Cryo EM<br />
**[[6c26]], [[6ezn]], [[7oci]], [[8agb]], [[8agc]] – yGT – Cryo EM<br />
**[[8age]] – yGT + peptide – Cryo EM<br />
**[[2lgz]] – yGT subunit STT3P – NMR<br />
**[[1rkl]] – yGT subunit Ost4p – NMR<br />
**[[3g7y]], [[3g9b]], [[3ga4]] – yGT subunit Ost6<br />
**[[3waj]], [[3wak]] – AfGT – ''Archaeoglobus fulgidus''<br />
**[[5gmi]] – AfGT + peptide<br />
**[[7e9s]] – AfGT + peptide + dolicol-P<br />
**[[3wai]] – AfGT C-terminal <br />
**[[3wov]] – GT C-terminal – ''Pyrococcus abyssi''<br />
*Lipopolysaccharide 1,6-galactosyltransferase
**[[6y6g]] - StBGT – ''Salmonella typhimurium''<br />
**[[6y6i]] - StBGT + UDP<br />
}}
}}


[[Category:Topic Page]]
[[Category:Topic Page]]

Latest revision as of 09:41, 29 March 2026

3D structures of glycosyltransferase

Updated on 29-March-2026

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Openfox

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