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==Electron cryo-microscopy of F420-reducing NiFe hydrogenase Frh==
==Electron cryo-microscopy of F420-reducing NiFe hydrogenase Frh==
<StructureSection load='4ci0' size='340' side='right'caption='[[4ci0]], [[Resolution|resolution]] 3.36&Aring;' scene=''>
<SX load='4ci0' size='340' side='right' viewer='molstar' caption='[[4ci0]], [[Resolution|resolution]] 3.36&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ci0]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_marburgensis Methanothermobacter marburgensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CI0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CI0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ci0]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermobacter_marburgensis Methanothermobacter marburgensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CI0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CI0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.36&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Coenzyme_F420_hydrogenase Coenzyme F420 hydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.12.98.1 1.12.98.1] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ci0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ci0 OCA], [http://pdbe.org/4ci0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ci0 RCSB], [http://www.ebi.ac.uk/pdbsum/4ci0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ci0 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ci0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ci0 OCA], [https://pdbe.org/4ci0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ci0 RCSB], [https://www.ebi.ac.uk/pdbsum/4ci0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ci0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/D9PYF9_METTM D9PYF9_METTM]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</SX>
[[Category: Coenzyme F420 hydrogenase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Methanothermobacter marburgensis]]
[[Category: Methanothermobacter marburgensis]]
[[Category: Allegretti, M]]
[[Category: Allegretti M]]
[[Category: Kuehlbrandt, W]]
[[Category: Kuehlbrandt W]]
[[Category: McMullan, G]]
[[Category: McMullan G]]
[[Category: Mills, D J]]
[[Category: Mills DJ]]
[[Category: Vonck, J]]
[[Category: Vonck J]]
[[Category: Electron transfer]]
[[Category: Ferredoxin]]
[[Category: Flavoprotein]]
[[Category: Oxidoreductase]]