6wtp: Difference between revisions

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'''Unreleased structure'''


The entry 6wtp is ON HOLD
==Human JAK2 JH1 domain in complex with PROTAC-intermediate linker handle 3==
<StructureSection load='6wtp' size='340' side='right'caption='[[6wtp]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WTP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WTP FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene>, <scene name='pdbligand=U8P:tert-butyl+4-[(4-{1-[3-(cyanomethyl)-1-(ethylsulfonyl)azetidin-3-yl]-1H-pyrazol-4-yl}-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino]benzoate'>U8P</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wtp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wtp OCA], [https://pdbe.org/6wtp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wtp RCSB], [https://www.ebi.ac.uk/pdbsum/6wtp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wtp ProSAT]</span></td></tr>
</table>


Authors: Yu, S., Nithianantham, S., Fischer, M.
==See Also==
 
*[[Janus kinase 3D structures|Janus kinase 3D structures]]
Description: Crystal Structure of Janus Kinase 2 in complex with a baricitinib based PROTAC
__TOC__
[[Category: Unreleased Structures]]
</StructureSection>
[[Category: Yu, S]]
[[Category: Large Structures]]
[[Category: Fischer, M]]
[[Category: Fischer M]]
[[Category: Nithianantham, S]]
[[Category: Nithianantham S]]
[[Category: Yu S]]

Latest revision as of 09:16, 9 October 2024

Human JAK2 JH1 domain in complex with PROTAC-intermediate linker handle 3

6wtp, resolution 2.50Å

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