TGF-beta receptor 3D structures

Updated on 17-December-2023 - For a general description of the protein see TGF-beta receptor

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• TGF-β receptor I; Domains: extracellular 33-112; kinase 200-503
  • 1ias, 5e8s – hTGFR-I kinase domain – human
    
  • 5e8t, 5e8u – hTGFR-I kinase domain (mutant)
    
  • 5e8w, 5e8x – hTGFR-I kinase domain (mutant) + staurosporine
    
  • 2l5s – hTGFR-I extracellular domain - NMR
    
  • 1b6c – hTGFR-I kinase domain + FKBP12
    
  • 1py5, 3faa, 3gxl, 3hmm, 2wot, 2wou, 3kcf, 2x7o, 3tzm, 4x0m, 4x2j, 4x2k, 4x2n, 5qim, 5fri, 4x2g, 4x2f, 5usq – hTGFR-I kinase domain + inhibitor
    
  • 5e8z, 5qik, 5qil, 5qtz, 5qu0, 6b8y, 5e90 – hTGFR-I kinase domain (mutant) + inhibitor
    
  • 1vjy – hTGFR-I residues 1-303 + inhibitor
    
  • 5e8x, 5e8w – hTGFBR-I kinase domain (mutant) + staurosporine
    
  • 1rw8 – hTGFR-I truncated kinase domain + inhibitor
    
  • 6mac – hTGFR-I extracellular domain + GDF-11 + activin receptor 2B-
    
• TGF-β receptor II
  • 1m9z – hTGFR-II extracellular domain
    
  • 1plo, 4p7u – hTGFR-II extracellular domain (mutant) - NMR
    
  • 4xjj – hTGFR-II extracellular domain (mutant) + inhibitor
    
  • 5e8v – hTGFR-II kinase domain (mutant)
    
  • 5e8y – hTGFR-II kinase domain (mutant) + staurosporine
    
  • 5e92 – hTGFR-II kinase domain (mutant) + AMPPNP
    
  • 5qin, 5e91, 7dv6 – hTGFR-II kinase domain + inhibitor
    
  • 1ktz – hTGFR-II extracellular domain + TGF-β3
    
  • 5ty4 – hTGFR-II extracellular domain + mmTGF-β2
    
  • 5tx4 – mTGFR-II extracellular domain (mutant) + hTGF-β2 - mouse
    
  • 1ks6 – cTGFR-II extracellular domain - chicken
    
• TGF-β receptor III
  • 7lbg – hTGFR-III + cytomegalovirus envelope glycoprotein + antibody – Cryo EM
    
  • 3qw9 – TGFR-III ZP-C domain - rat
    
  • 4ajv – mTGFR-III ZP-C domain
    
• TGF-β receptor I+II
  • 2pjy – hTGFR-I extracellular domain (mutant) + hTGFR-II extracellular domain (mutant) + TGF-β3
    
  • 3kfd – hTGFR-I extracellular domain + hTGFR-II extracellular domain + TGF-β1
    

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