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==Solution NMR Structure of a putative Uracil DNA glycosylase from Methanosarcina acetivorans, Northeast Structural Genomics Consortium Target MvR76==
==Solution NMR Structure of a putative Uracil DNA glycosylase from Methanosarcina acetivorans, Northeast Structural Genomics Consortium Target MvR76==
<StructureSection load='2l3f' size='340' side='right'caption='[[2l3f]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2l3f' size='340' side='right'caption='[[2l3f]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2l3f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_35395 Atcc 35395]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L3F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L3F FirstGlance]. <br>
<table><tr><td colspan='2'>[[2l3f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanosarcina_acetivorans Methanosarcina acetivorans]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L3F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L3F FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MA_0462 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2214 ATCC 35395])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l3f OCA], [https://pdbe.org/2l3f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l3f RCSB], [https://www.ebi.ac.uk/pdbsum/2l3f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l3f ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l3f OCA], [https://pdbe.org/2l3f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l3f RCSB], [https://www.ebi.ac.uk/pdbsum/2l3f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l3f ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HDG_METAC HDG_METAC] Excises hypoxanthine, a deamination product of adenine, from double-stranded DNA. Acts on double-stranded DNA containing G/I, T/I, A/I and C/I base pairs, but not on single-stranded inosine-containing DNA. Has also minor xanthine DNA glycosylase activity. Lacks any detectable uracil-DNA glycosylase activity.<ref>PMID:21642431</ref>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 35395]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Acton, T B]]
[[Category: Methanosarcina acetivorans]]
[[Category: Aramini, J M]]
[[Category: Acton TB]]
[[Category: Ciccosanti, C T]]
[[Category: Aramini JM]]
[[Category: Everett, J K]]
[[Category: Ciccosanti CT]]
[[Category: Hamilton, K]]
[[Category: Everett JK]]
[[Category: Lee, H W]]
[[Category: Hamilton K]]
[[Category: Montelione, G T]]
[[Category: Lee HW]]
[[Category: Structural genomic]]
[[Category: Montelione GT]]
[[Category: Rost, B]]
[[Category: Rost B]]
[[Category: Wang, H]]
[[Category: Wang H]]
[[Category: Xiao, R]]
[[Category: Xiao R]]
[[Category: PSI, Protein structure initiative]]
[[Category: Psi-biology]]
[[Category: Unknown function]]
Retrieved from "https://proteopedia.org/2l3f"